Cleaver Lab


Our lab focuses on the molecular and cellular mechanisms underlying cell fate specification during blood vessel development and organogenesis.

Meet the PI

Ondine Cleaver portrait

Ondine Cleaver, Ph.D.

Dr. Cleaver joined UT Southwestern’s Molecular Biology as faculty in late 2004 and was promoted to Associate Professor in 2010.

Her lab studies cell fate and how cells assemble into tissues. Her group is particularly interested in intracellular signaling events that drive cytoskeletal or adhesion changes within progenitor cells, allowing them to assemble into functional tissues. She focuses on blood vessels and on developing organs, such as the pancreas, the kidney, and the lung. She is interested in how cues in the microenvironment drive vascular assembly or growth, and how blood vessels in turn communicate paracrine, non-nutritional signals to stem cell niches.

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