Publications

Featured Publications

Epithelial dynamics of pancreatic branching morphogenesis.

Villasenor A, Chong DC, Henkemeyer M, Cleaver O. December 2010 Dec;137(24) 4295-305

Blood vessel tubulogenesis requires Rasip1 regulation of GTPase signaling.

Xu K, Sacharidou A, Fu S, Chong DC, Skaug B, Chen ZJ, Davis GE, Cleaver O. April 2011 Apr 19;20(4) 526-39

Rasip1 is essential to blood vessel stability and angiogenic blood vessel growth.

Koo Y, Barry DM, Xu K, Tanigaki K, Davis GE, Mineo C, Cleaver O 2016 Feb Angiogenesis

Cdc42 and k-Ras Control Endothelial Tubulogenesis through Apical Membrane and Cytoskeletal Polarization: Novel Stimulatory Roles for GTPase Effectors, the Small GTPases, Rac2 and Rap1b, and Inhibitory Influence of Arhgap31 and Rasa1.

Norden PR, Kim DJ, Barry DM, Cleaver OB, Davis GE 2016 PLoS ONE 1 11 e0147758

Endosomal sorting of Notch receptors through COMMD9-dependent pathways modulates Notch signaling.

Li H, Koo Y, Mao X, Sifuentes-Dominguez L, Morris LL, Jia D, Miyata N, Faulkner RA, van Deursen JM, Vooijs M, Billadeau DD, van de Sluis B, Cleaver O, Burstein E 2015 Nov J. Cell Biol. 3 211 605-17

Vascular patterning: coordinated signals keep blood vessels on track.

Meadows SM, Cleaver O 2015 Mar Curr. Opin. Genet. Dev. 32C 86-91

Pdx1 regulates pancreas tubulogenesis and E-cadherin expression.

Marty-Santos L, Cleaver O 2015 Dec Development

Progenitor Epithelium: Sorting Out Pancreatic Lineages.

Marty-Santos L, Cleaver O 2015 Aug J. Histochem. Cytochem. 8 63 559-74

Wnt4 Is essential to normal mammalian lung development.

Caprioli A, Villasenor A, Wylie LA, Braitsch C, Marty-Santos L, Barry D, Karner CM, Fu S, Meadows SM, Carroll TJ, Cleaver O 2015 Aug Dev. Biol.

Cdc42 is required for cytoskeletal support of endothelial cell adhesion during blood vessel formation.

Barry DM, Xu K, Meadows SM, Zheng Y, Norden PR, Davis GE, Cleaver O 2015 Aug Development

Annexin A3 Regulates Early Blood Vessel Formation.

Meadows SM, Cleaver O 2015 PLoS ONE 7 10 e0132580

Outside in: inversion of cell polarity controls epithelial lumen formation.

Davis GE, Cleaver OB 2014 Oct Dev. Cell 2 31 140-2

Autophagy is essential for cardiac morphogenesis during vertebrate development.

Lee E, Koo Y, Ng A, Wei Y, Luby-Phelps K, Juraszek A, Xavier RJ, Cleaver O, Levine B, Amatruda JF 2014 Jan Autophagy 4 10

Bone morphogenetic protein 2 signaling negatively modulates lymphatic development in vertebrate embryos.

Dunworth WP, Cardona-Costa J, Bozkulak EC, Kim JD, Meadows S, Fischer JC, Wang Y, Cleaver O, Qyang Y, Ober EA, Jin SW 2014 Jan Circ. Res. 1 114 56-66

Tcf19 is a novel islet factor necessary for proliferation and survival in the INS-1 beta cell line.

Krautkramer KA, Linnemann AK, Fontaine DA, Whillock AL, Harris TW, Schleis GJ, Truchan NA, Marty-Santos L, Lavine JA, Cleaver O, Kimple ME, Davis DB 2013 Jul Am. J. Physiol. Endocrinol. Metab.

Resolution of defective dorsal aortae patterning in Sema3E deficient mice occurs via angiogenic remodeling.

Meadows SM, Ratliff LA, Singh MK, Epstein JA, Cleaver O 2013 Feb Dev. Dyn.

Vascular endothelial growth factor receptor-2 promotes the development of the lymphatic vasculature.

Dellinger MT, Meadows SM, Wynne K, Cleaver O, Brekken RA 2013 PLoS ONE 9 8 e74686

EphB3 marks delaminating endocrine progenitor cells in the developing pancreas.

Villasenor A, Marty-Santos L, Dravis C, Fletcher P, Henkemeyer M, Cleaver O 2012 May Dev. Dyn. 5 241 1008-19

Integration of repulsive guidance cues generates avascular zones that shape mammalian blood vessels.

Meadows SM, Fletcher PJ, Moran C, Xu K, Neufeld G, Chauvet S, Mann F, Krieg PA, Cleaver O 2012 Jan Circ. Res. 1 110 34-46

Vascular instruction of pancreas development.

Cleaver O, Dor Y 2012 Aug Development 16 139 2833-43

Crosstalk between the developing pancreas and its blood vessels: an evolving dialog.

Villasenor A, Cleaver O 2012 Aug Semin. Cell Dev. Biol. 6 23 685-92

The developing endothelium in action.

Cleaver O 2011 Oct

Blood vessels restrain pancreas branching, differentiation and growth.

Magenheim J, Ilovich O, Lazarus A, Klochendler A, Ziv O, Werman R, Hija A, Cleaver O, Mishani E, Keshet E, Dor Y 2011 Nov Development 21 138 4743-52

Tubulogenesis during blood vessel formation.

Xu K, Cleaver O 2011 May

Stepwise arteriovenous fate acquisition during mammalian vasculogenesis.

Chong DC, Koo Y, Xu K, Fu S, Cleaver O 2011 Jul 2153-65

HoxA3 is an apical regulator of haemogenic endothelium.

Iacovino M, Chong D, Szatmari I, Hartweck L, Rux D, Caprioli A, Cleaver O, Kyba M 2011 Jan Nat. Cell Biol. 1 13 72-8

Rgs16 and Rgs8 in embryonic endocrine pancreas and mouse models of diabetes.

Villasenor A, Wang ZV, Rivera LB, Ocal O, Asterholm IW, Scherer PE, Brekken RA, Cleaver O, Wilkie TM 2010 Sep-Oct Dis Model Mech 9-10 3 567-80

Endothelial-specific expression of WNK1 kinase is essential for angiogenesis and heart development in mice.

Xie J, Wu T, Xu K, Huang IK, Cleaver O, Huang CL 2009 Sep Am. J. Pathol. 3 175 1315-27

Rasip1 is required for endothelial cell motility, angiogenesis and vessel formation.

Xu K, Chong DC, Rankin SA, Zorn AM, Cleaver O 2009 May Dev. Biol. 2 329 269-79

Dependence of mouse embryonic stem cells on threonine catabolism.

Wang J, Alexander P, Wu L, Hammer R, Cleaver O, McKnight SL 2009 Jul Science 5939 325 435-9

Blood vessel tubulogenesis requires Rasip1 regulation of GTPase signaling.

Xu K, Sacharidou A, Fu S, Chong DC, Skaug B, Chen ZJ, Davis GE, Cleaver O 2011 Apr Dev. Cell 4 20 526-39

Epithelial dynamics of pancreatic branching morphogenesis.

Villasenor A, Chong DC, Henkemeyer M, Cleaver O 2010 Dec Development 24 137 4295-305

Ligand-induced EpoR internalization is mediated by JAK2 and p85 and is impaired by mutations responsible for primary familial and congenital polycythemia.

Sulahian R, Cleaver O, Huang LJ 2009 May Blood 21 113 5287-97

BMP and BMP receptor expression during murine organogenesis.

Danesh SM, Villasenor A, Chong D, Soukup C, Cleaver O 2009 Jun Gene Expr. Patterns 5 9 255-65

Biphasic Ngn3 expression in the developing pancreas.

Villasenor A, Chong DC, Cleaver O 2008 Nov Dev. Dyn. 11 237 3270-9

Prospective isolation of skeletal muscle stem cells with a Pax7 reporter.

Bosnakovski D, Xu Z, Li W, Thet S, Cleaver O, Perlingeiro RC, Kyba M 2008 Dec Stem Cells 12 26 3194-204

Prospective isolation and global gene expression analysis of definitive and visceral endoderm.

Sherwood RI, Jitianu C, Cleaver O, Shaywitz DA, Lamenzo JO, Chen AE, Golub TR, Melton DA 2007 Apr Dev. Biol. 2 304 541-55

Blood vessel signals during development and beyond.

Cleaver O 2004 Curr. Top. Dev. Biol. 62 1-36

Endothelial signaling during development.

Cleaver O, Melton DA 2003 Jun Nat. Med. 6 9 661-8

Role of endothelial cells in early pancreas and liver development.

Lammert E, Cleaver O, Melton D 2003 Jan Mech. Dev. 1 120 59-64

Endothelial signaling during development.

Cleaver, O. and Melton, D.A. 2003 9 661-668

Induction of pancreatic differentiation by signals from blood vessels.

Lammert E, Cleaver O, Melton D 2001 Oct Science 5542 294 564-7

Notochord patterning of the endoderm.

Cleaver O, Krieg PA 2001 Jun Dev. Biol. 1 234 1-12

Notochord patterning of the endoderm.

Cleaver, O. and Krieg, P.A. 2001 234 1-12

Induction of pancreatic differentiation by signals from blood vessels.

Lammert, E.*, Cleaver, O.* and Melton, D. 2001 294 564-567

Distinct expression patterns for two Xenopus Bar homeobox genes.

Patterson KD, Cleaver O, Gerber WV, White FG, Krieg PA 2000 Mar Dev. Genes Evol. 3 210 140-4

Endoderm patterning by the notochord: development of the hypochord in Xenopus.

Cleaver O, Seufert DW, Krieg PA 2000 Feb Development 4 127 869-79

Expression from DNA injected into Xenopus embryos.

Cleaver O, Krieg PA 1999 Methods Mol. Biol. 127 133-53

VEGF mediates angioblast migration during development of the dorsal aorta in Xenopus.

Cleaver O, Krieg PA 1998 Oct Development 19 125 3905-14

Homeobox genes in cardiovascular development.

Patterson KD, Cleaver O, Gerber WV, Grow MW, Newman CS, Krieg PA 1998 Curr. Top. Dev. Biol. 40 1-44

Neovascularization of the Xenopus embryo.

Cleaver O, Tonissen KF, Saha MS, Krieg PA 1997 Sep Dev. Dyn. 1 210 66-77

Xbap, a vertebrate gene related to bagpipe, is expressed in developing craniofacial structures and in anterior gut muscle.

Newman CS, Grow MW, Cleaver O, Chia F, Krieg P 1997 Jan Dev. Biol. 2 181 223-33

Overexpression of the tinman-related genes XNkx-2.5 and XNkx-2.3 in Xenopus embryos results in myocardial hyperplasia.

Cleaver OB, Patterson KD, Krieg PA 1996 Nov Development 11 122 3549-56