The main research focus of the Otwinowski lab is on developing computational and statistical
methods and protocols for macromolecular structure determination using X-ray crystallography.

The Nam lab asks how the shape of an RNA regulates its function. We study the biochemical and structural mechanisms in RNA-mediated gene regulation pathways important for normal and disease states.

 In diseases like cancer, signaling pathways can be corrupted by mutations that cause the cells to grow and spread uncontrollably. Our lab is interested in understanding how these defective pathways reprogram cellular metabolism to drive cancer growth.

We use theoretical methods to study proteins, genomes and organisms.

The Wetzel Lab targets critical steps in the parasite’s life cycle in order to develop therapeutics for Leishmaniasis.

Our lab seeks to uncover the structure-function relationship of macromolecules involved in protein misfolding — a key element of Alzheimer’s and other neurodegenerative diseases.

We are interested in building small organic molecules and studying their functions in biological systems. Our lab started in 2004 using state-of-the-art tools to address challenging issues in the field of natural product synthesis. 

Glen Liszczak  laboratory is exploring cellular signaling mechanisms that regulate transcription and preserve genome stability.

The Smith Lab strives to develop enabling tools for organic synthesis, allowing bioactive molecules of great complexity to be prepared in a concise and sustainable fashion.

The ultimate goal of the Nijhawan-De Branander Lab is to discover first in class drugs for the treatment of cancer.