Leveraging powerful new cell-based and cell-free systems, high-speed fluorescence imaging, and in vitro reconstitution using purified components to understand how cellular organelles such as peroxisomes are formed, how they acquire their unique identities and functions, and how defects in these processes cause human disease.

Leveraging cutting-edge genetic and chemical screens to uncover novel and enhanced therapeutics for cancer treatment.

Deja Lab is dedicated to advancing the field of metabolomics and fluxomics in metabolic disease research.

The Wang lab applies single-molecule fluorescence biophysical, quantitative biochemical, structural, and genetics approaches to unravel the intricate relationships between structure, dynamics and function in complex dynamic biological systems. Our primary goal is to understand the dynamic mechanisms of cytosolic and mitochondrial protein synthesis and how they are dysregulated in human diseases.

We are investigating how protein homeostasis (the maturation and turnover of enzymes) interacts with lipid homeostasis.

The Tu Lab is investigating how a variety of cellular processes and decisions are coordinated with metabolic state, and how the dysregulation of these mechanisms might be linked to disease and aging.

We aim to globally understand how the physical and chemical properties of materials affect interactions with biological systems in the context of improving therapies.

We investigate the mechanism of neurotransmitter release using a variety of biophysical approaches, including NMR spectroscopy, X-ray crystallography, cryo-EM, molecular dynamics simulations and liposome fusion assays.

The Rice Lab uses structure, biochemistry, reconstitution, microscopy, computer modeling, and more to study the molecular mechanisms that generate and regulate microtubule dynamics.

Our lab is broadly focused on the cellular signaling that drives the interactions between the intracellular parasite Toxoplasma gondii and its varied hosts.