While cardiac and thoracic surgeries are often life-saving and may invoke life-changing improvements in health related quality of life, many patients also experience varying degrees of end organ injury and associated complications that can persist in the years following surgery. In 2014 Amanda Fox, M.D., M.P.H. initiated a genomics, biomarkers and outcomes research group at UTSW. This group values multi-specialty collaborations between anesthesiologists, surgeons cardiologists, radiologists, critical care physicians, biostatisticians, geneticists, bench scientists, and many other specialties.

Kong lab aims to harness the cutting-edge technologies in human genetics and genomics, immunology, and molecular biology to better understand the pathogenesis of gastrointestinal inflammation.

The focus of our current research is the biochemistry and molecular characterization of ABCG5/ABCG8 transporter, aiming at understanding the mechanism by which this transport system operates to translocate cholesterol cross membranes.

Mootha Lab uses human genetics and genomics to understand the molecular basis of Fuchs' endothelial corneal dystrophy and develop novel therapeutic strategies.

The ultimate goal of the Kittler Lab's research is to develop novel therapeutic approaches that target transcription factors, which play important roles in common solid tumors (brain, breast, lung and prostate cancer) and could therefore have translational potential.

Our goal is to provide state-of-the-art expertise for analysis of exome and genome sequencing.

Our research program focuses on understanding how dysregulation of lipid uptake and trafficking contributes to human diseases. 

The Glass lab focuses on how genes regulate skin development and function by studying how gene mutations or abnormal gene expression lead to skin disease.

Dr. Gray is overseeing one of the nation’s few facilities that manufactures a special type of gene-delivering virus for patient use.

The Bioinformatics Lab provides services to manage and analyze next-generation sequencing data.