We are investigating how protein homeostasis (the maturation and turnover of enzymes) interacts with lipid homeostasis.

Jan’s Lab is interested in understanding the dynamics of protein-RNA complexes during ribosome biogenesis. We are particularly focused on the roles of ATPases in coordinating ribosomal RNA processing and remodeling events, as well as the importance of these enzymes in signaling between the ribosome biogenesis pathway and the cell cycle machinery.

Saelices Lab employs crystallography and cryo-EM to study amyloid deposition and design anti-amyloid tools.

The Rosen Lab seeks to understand the formation, regulation, functions and internal structures of membraneless cellular compartments termed biomolecular condensates.