The major interest of my lab is to understand the transcriptional regulatory mechanisms involved in human diseases with a focus on cardiovascular diseases and cancer. 

The Liu Lab studies the seasonal clock and its roles in human health. We use a new seasonal primate model, the mouse lemur, and an interdisciplinary approach of molecular biology, genetics, omics, machine learning, and computational modeling. We also apply the mouse lemur primate model to study pathophysiology that is poorly represented in mice, with a focus on neurodegeneration, immunology, and metabolism.

The Bann Laboratory focuses on discovering novel mechanistic targets to treat heart failure. We aim to identify regulators of cardiac cell fate reprogramming and regeneration as a molecular strategy to repair and heal the heart following injury.

Muto lab leverages both cutting-edge wet-lab and multi-omics approaches to understand gene regulatory mechanism driving kidney diseases. Current projects are focused on acute kidney injury and polycystic kidney disease.

The Lee Lab is dedicated to leveraging human and molecular genetics to explore the complex interactions between cells and the surrounding extracellular matrix, with a particular focus on cardiovascular development and disease. 

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We unite researchers with diverse expertise in computational modeling, biochemical reconstitution, structural analysis of polymers, and cell biology to focus on three distinct condensates that are important for genome homeostasis.

Qi lab specializes in investigating the structure and function of membrane proteins related to human diseases using cryo-EM, cell-based assays, and mouse models.

The Lin Lab studies the transformation of brief experiences into enduring memories, their impact on behaviors, and the differing responses seen in both healthy and diseased conditions. Utilizing a multidisciplinary approach, our research explores how experience-induced genetic programs establish connections between experiences and synaptic modifications within neural circuits, ultimately driving persistent behavioral changes.

Research lab led by PI Faith (Yuanyuan) Zhang, M.D., Ph.D.