Dr. Song's laboratory focuses on understanding the mechanisms of cell death, including apoptosis, ferroptosis, pH-dependent cell death, and immunogenic cell death.

Under the guidance of director Dr. Daolin Tang, the research group focuses on basic, translational and clinical application research on damage-associated molecular patterns (DAMPs) signaling pathways. Inflammation is a fundamental response to infection and injury in all multicellular organisms. The danger hypothesis states that endogenous molecules (protein and non-protein) released during cell death or tissue damage can trigger inflammation in the absence of infection, collectively referred to as DAMPs. We are particularly interested in elucidating the molecular mechanisms underlying stress-induced cellular defense and cell death signaling in normal and cancer cells, and how release of DAMPs modulates immune responses in disease.

The Tower lab integrates multi-omics-based approaches in the fields of musculoskeletal development, homeostasis, repair and regeneration. 

Research conducted by the Nomellini Lab utilizes animal models as well as human samples to examine the interaction between the innate and adaptive immune responses that occur after injury or infection, and the heterogeneity of the immune responses that occur in each individual. Led by Vanessa Nomellini, M.D., Ph.D., our lab ultimately aims to develop personalized immune therapies to reverse the immunosuppression that can occur in ICU survivors.

The research of the Huang Laboratory focuses on understanding the function of fibroblast progenitor cells and fibroblasts in regulating the immune system.

Our mission is to understand the most fundamental questions in cancer biology, such as tumor initiation, progession, and response to therapy, through state-of-the-art experimentation, fruitful collaborations and, above all, out-of-the box thinking to develop novel, safe(r) and more effective therapies to win the fight against cancer!

Our mission is to improve the lives of people living with skin and musculoskeletal diseases through rigorous science and compassion.

The work of Deborah Carlson, Ph.D., focuses on characterizing the inflammasome mediating the inflammatory response in the heart following thermal injury and thermal injury complicated with sepsis. 

Publications for Dr. Emina Huang's Lab

The Dellinger Laboratory studies the development of the lymphatic vasculature and diseases caused by errors in the development of lymphatic vessels.