Leveraging cutting-edge genetic and chemical screens to uncover novel and enhanced therapeutics for cancer treatment.

How do cells sense metabolites to drive their growth and proliferation?  We seek to study metabolites not only as nutrients but as cellular instruction signals that dictate cell biology. 

Our lab is creating better experimental models that reveal how cancer cells metastasize and evade our immune system. We use these models to develop new drugs that engage our immune system to kill cancer cells.

Our primary goal in Sieber Lab is to understand the dynamic changes in metabolic programs that support developmental and disease progression. 

Zaki Lab's research focuses on the the study of gastrointestinal inflammation and cancer.

The Kraus Lab is interested in the basic mechanisms of nuclear signaling and gene regulation by small molecules and how these signaling pathways relate to human physiology and disease states.

The ultimate goal of the Nijhawan-De Branander Lab is to discover first in class drugs for the treatment of cancer. 

The Wang Lab studies neurodegeneration and cell death induced by brain injury, mitochondrial dysfunction, and/or genome instability.

We use genetic systems to deconstruct functions associated with the most commonly mutated genes found in human cancers.

We use live-cell microscopy, nano-rheology, and synthetic biology to understand oocyte ageing, embryogenesis, and cancer onset.