News

March 2026

Dr. Cheng Zhang Receives a Scholar-in-Training Award for the AACR Special Conference in Cancer Research

Congratulations to Cheng Zhang, who received a Scholar-in-training award for AACR Special Conference in Cancer Research: Innovations in Kidney Cancer Research: From Molecular Insights to Therapeutic Breakthroughs, which was held from March 13th-March 16th, 2026 in Philadelphia, PA.

May 2025

Dr. Qing Zhang Awarded DoD Grant

The project aims to identify and validate novel “hidden drivers” in clear cell renal cell carcinoma (ccRCC) using advanced systems biology approaches. This work will investigate the role of NEK5 in tumor progression and explore new therapeutic strategies, including PROTAC-based degraders, to improve treatment outcomes for kidney cancer patients.

More About this Research

March 2025

Dr. Jun Fang and Dr. Tao “Dylan” Wang Received DoD KCRP Fellowship Awards

Dr. Jun Fang from Dr. Qing Zhang’s lab was recognized for her work on HIF-2α regulation in ccRCC. Her research focuses on Suppressor of Cytokine Signaling 3 (SOCS3) and its role in controlling HIF-2α through the JAK-STAT pathway. Her findings could lead to alternative treatment options for patients resistant to current HIF-2α inhibitors like Belzutifan.
Dr. Tao “Dylan” Wang, also from Dr. Zhang’s lab, received this funding for his research using CRISPR screening to identify oncogenic enhancers in ccRCC. His work highlights a novel PLXNA1 gene enhancer that drives tumor growth, with potential therapeutic implications for targeting ccRCC at the epigenetic level.

More About this Research

June 2024

Dr. Chengheng Liao Receives Society of Urologic Oncology Specialized Programs of Research Excellence Award

Dr. Chengheng Liao received support for a two-year research project titled “Investigation of BBOX1 as a novel tumor suppressor in ccRCC” at UT Southwestern, under the mentorship Qing Zhang, PhD.

More About this Research

August 2023

Dr. Qing Zhang receives 2024 ASIP Outstanding Investigator Award

His research focuses on how cancer cells adapt to low-oxygen environments, driving tumor growth and resistance to therapy. His team has identified novel pathways and therapeutic targets in breast and kidney cancers. These findings may lead to new treatment strategies for cancer patients.

More About this Research

April 2023

Dr. Jin Zhou Receives 2022 AACR–Exelixis Renal Cell Carcinoma Research Fellowship

Dr. Jin Zhou has been awarded the 2022 AACR–Exelixis Renal Cell Carcinoma Research Fellowship by the American Association for Cancer Research (AACR). This fellowship supports innovative research aimed at advancing the understanding and treatment of kidney cancer. Her project, titled “RBM39-DGAT1 Axis is an Oncogenic Driver in Clear Cell Renal Cell Carcinoma,” focuses on uncovering key molecular mechanisms driving tumor progression. Her work may provide new insights into therapeutic targets and contribute to the development of more effective treatments for patients with clear cell renal cell carcinoma.

More About this Research

July 2020

Triple negative breast cancer meets its match

BBOX1 enzyme could serve as a drug target for the deadly subset of breast cancer.

More About this Research

July 2020

UTSW researchers uncover new vulnerability in kidney cancer

In their investigation of the most common type of kidney cancer, called clear cell renal cell carcinoma (ccRCC), Qing Zhang, Ph.D., and his colleagues identified a possible way to treat tumors while sparing nearby healthy tissue.

Read the Feature