Our laboratory seeks to gain new insights into the unique biology of germ cells, using a variety of genetic, molecular, biochemical, and live-cell-imaging methods.
We are currently focusing on how germ cells regulate the translation of their transcriptomes, interact with their niche and other somatic cell neighbors, and preserve the integrity of their genomes. We hope our discoveries will lead to understanding how perturbations in normal gene function cause disease.
We are also interested in the homeostasis and heterogeneity of ribosomes in a variety of contexts, including human organoids.