Training

Postdoctoral Fellow in Transcription, Chromatin, Epigenetics, HPV, Molecular Virology, Cancer Biology, and Small Compound Inhibitors

Research Areas:

  • Molecular Virology

  • Cancer Biology

  • Transcription

  • Chromatin

  • Gene Regulation

  • Epigenetic Control

  • Post-translational Modification

A postdoctoral training position is available at the Chiang Lab to study:

  • breast cancer

  • human papillomavirus (HPV)

  • mechanism of chromatin-dependent transcription

  • post-translational modification of transcription factors

  • cofactors and the general transcription machinery

  • cancer biology

  • small compound development

Our current interest is to understand the molecular basis of the epigenetic reader protein BRD4 in transcription programming, DNA repair, and cancer pathway selectivity. We aim to further develop small compound inhibitors to block the oncogenic function of BRD4 using biochemical, molecular, genetic, chemical biology, and genomic approaches with in vitro-reconstituted chromatin transcription, cell-based, and inducible knockout and knock-in transgenic mouse disease models. Breast cancer and HPV are two disease models presently pursued in the lab.

Applicants with a recent Ph.D. degree and a strong background in transcription, chromatin, protein biochemistry, molecular biology, virology, chemical biology, mouse models, genomics, and proteomics are encouraged to apply. Expertise in animal work is preferred but not essential.

Information on the UT Southwestern postdoctoral training program and benefits can be found in the Postdoc Handbook.

Interested individuals should send a CV, statement of interests, and a list of three references to:

Cheng-Ming Chiang, Ph.D.
UT Southwestern Medical Center
5323 Harry Hines Blvd.
Dallas, TX 75390-8807
Email

Graduate Student

Graduate students looking for research experience as part of their rotation are welcome to work in the Chiang Lab! We hope you will consider us in your pursuit of professional training.

Professor Chiang is affiliated with Cancer Biology and Cell and Molecular Biology Graduate Programs.

If interested, please contact Dr. Chiang for more information.

Cheng-Ming Chiang, Ph.D.
UT Southwestern Medical Center
5323 Harry Hines Blvd.
Dallas, TX 75390-8807
Email