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A major focus of the Patwardhan Lab is translational research into mechanisms of pain and potential treatment.

We are interested in taking bioinformatics and data integration approaches to gain insights into cancer metabolism, inborn errors of metabolism, and lung neoplasm.

Sakano Lab investigates FMRP's influence on auditory brainstem development in Fragile X Syndrome. We examine gene expression and its potential link to autism, auditory processing, hyperacusis, and tinnitus.

The Ranjan Lab’s mission is to develop and translate novel immunotherapies, with a particular focus on addressing malignant cancers in humans and animals.

We are broadly interested in how energy is regulated on a systems level during infection. Our current projects are focused on understanding the role that adipose tissue plays in the response to influenza and SARS-CoV2.

We seek to understand how RNA/protein assemblies control cellular states, and how related pathways are hijacked by diseases of aging.

Interventional psychiatry is treatment that combines brain stimulation with medication for difficult-to-treat mental health disorders. At UT Southwestern Medical Center, our psychiatrists have advanced training and expertise in caring for people with treatment-resistant mental health disorders.

We specialize in the latest advances in brain stimulation to bring relief to people who haven’t had success with traditional treatments.

Please contact our team if planning neoadjuvant Adriamycin (doxorubicin), for enrollment in the HP Cardiotox Study.

Research lab led by PI Faith (Yuanyuan) Zhang, M.D., Ph.D.

The Luo lab studies hypoxia stress in human cancers with a focus on epigenetic and metabolic alterations. 

The Stopschinski lab investigates molecular and cellular mechanisms that drive neurodegeneration in Alzheimer’s Disease and other tauopathies with the goal to find new diagnostic and therapeutic approaches for these conditions.

The CDR Collaborative studies last mile delivery problems across the cancer control continuum to develop and implement solutions.

The Lin Lab studies the transformation of brief experiences into enduring memories, their impact on behaviors, and the differing responses seen in both healthy and diseased conditions. Utilizing a multidisciplinary approach, our research explores how experience-induced genetic programs establish connections between experiences and synaptic modifications within neural circuits, ultimately driving persistent behavioral changes.

The Hattori lab studies how neural circuits integrate sensorimotor information, memory, and internal state to guide behavior.

Our group initially investigated a novel immune checkpoint inhibitor targeting a rare heparan sulfate (rHS) in melanoma treatment. Collaboratively, we explored the potential of a single-domain humanized rHS antibody (1A7 clone) that inhibits DC-HIL function and also angiogenesis and chemokine effects linked to diverse cancer progression signaling pathways. This experience provided insights into rHS-targeting as a promising approach to melanoma therapy.

The overall goal of our laboratory is to discover the processes in endothelial cells that govern cardiovascular and metabolic health and disease. 

The Louros Lab uses a hybrid approach combining molecular biophysics, structural biology, and bioinformatics to investigate protein stability, misfolding, and aggregation, with a particular interest in neurodegenerative diseases.

We study bacterial RNA polymerase function and regulation.

The Noch Lab is a basic and translational research laboratory focused on identifying novel strategies to target metabolic vulnerabilities in glioma.

The Varadarajan Lab is interested in rebuilding neural circuits and restoring sensory function impaired by injury or disease.