Muto Lab
Muto lab leverages both cutting-edge wet-lab and multi-omics approaches to understand gene regulatory mechanism driving kidney diseases. Current projects are focused on acute kidney injury and polycystic kidney disease.
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Muto lab leverages both cutting-edge wet-lab and multi-omics approaches to understand gene regulatory mechanism driving kidney diseases. Current projects are focused on acute kidney injury and polycystic kidney disease.
The Gloeggler lab is interested in spin phenomena and explores how to use them as new contrast mechanism for magnetic resonance. One focus is on using parahydrogen, a spin isomer of hydrogen gas, and how to harvest its spin order to obtain signal enhanced/hyperpolarized contrast agents.
Our current research is focused on biochemical and structural studies of how membrane molecules signal to the actin cytoskeleton through a large, five-protein complex named the WAVE Regulatory Complex (WRC).
We investigate the neuroepigenetic mechanisms regulating synaptic plasticity in the hypothalamus, their role in maintaining body weight set-point, and how their dysregulation contributes to diet-induced obesity, weight-regain, and aging-related impairments in appetite.
Dr. Kang's research is dedicated to elucidating the molecular and immunological roles of damage-associated molecular patterns (DAMPs) and pattern recognition receptors (PRRs) in inflammatory diseases.
Leveraging powerful new cell-based and cell-free systems, high-speed fluorescence imaging, and in vitro reconstitution using purified components to understand how cellular organelles such as peroxisomes are formed, how they acquire their unique identities and functions, and how defects in these processes cause human disease.
The Connected Aging Lab is committed to advancing brain health and emotional well-being in older adults by developing inclusive, relationship-centered interventions that bridge science, clinical care, and community.
The Florian-Rodriguez Lab investigates the cellular and molecular mechanisms of pelvic organ prolapse.
The Mosley Lab develops and applies innovative genomic and informatics approaches to identify opportunities to use genetic background to inform clinical and public health decision-making, to identify risk factors and biomarkers of disease, and to identify and reduce heath inequities in vulnerable populations.
Castrillion Lab's work is aimed at understanding why endometrial or uterine cancers arise and spread, with an eye on prevention, earlier and more accurate diagnosis, improved treatments, and better overall patient outcomes.
The Singal & Rich research group focuses on generating critical insights to improve the entire spectrum of liver cancer care. Our studies involve assessing and promoting novel practices, imaging, and blood-based biomarkers to improve risk stratification, screening, early detection and outcomes for patients with hepatocellular carcinoma and other primary liver cancers.
The Mondal Lab employs computational genomics to characterize early molecular markers of retinal neurodegenerative diseases. We investigate gene networks' underlying retinal response to dietary risk factors linked to age-related disorders. We aim to understand retinal disease mechanisms and identify therapeutic targets and lifestyle interventions that support healthy vision.
Drapkin Lab investigates the molecular drivers of oncogenesis, metastasis, and chemoresistance in small cell lung cancer (SCLC) to discover new therapeutic targets.
The Bann Laboratory focuses on discovering novel mechanistic targets to treat heart failure. We aim to identify regulators of cardiac cell fate reprogramming and regeneration as a molecular strategy to repair and heal the heart following injury.
Using patient-specific stem cells, tissue engineering, and omics technologies to develop precision medicine for cardiovascular disease.
The Ortiz Lab develops advanced mathematical models and AI-driven approaches to understanding mood disorders as dynamic biological systems, works on nonlinear analysis of mood regulation, and integrates wearable technology with personalized treatment frameworks.
Liu (Shixuan) Lab
The overarching goal of the Liu Lab is to redefine membrane enzymology.
Ying Lab focuses on the development and clinical translation of soft medical devices, leveraging advanced design and fabrication techniques to tackle critical, unresolved challenges in human health. Current efforts in my lab center on hydrogel bioadhesives, soft medical robots, and ingestible bioelectronics aimed at enabling tissue-interfacing diagnostics and therapeutics in extreme body environments.
Our research focuses on genetic epilepsy and will help us understand the roles of genes such as ASH1L and SLC13A5 through clinical patient studies and mouse models, advancing treatment options for these disorders and deepening the understanding of epilepsy.