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research lab at UT Southwestern for Yun Wei, Ph.D.

Our research focuses on developing and translating computational neuroimaging methods to delineate human brain structure-function relationships. Current applications include identifying biomarkers of disease progression and treatment response in multiple sclerosis and other neurodegenerative diseases. 

Dr. Li's research focuses on gene-environment interactions in cardiometabolic disease and chronic kidney disease (CKD), providing crucial insights for precision health. 

Muto lab leverages both cutting-edge wet-lab and multi-omics approaches to understand gene regulatory mechanism driving kidney diseases. Current projects are focused on acute kidney injury and polycystic kidney disease.

The Gloeggler lab is interested in spin phenomena and explores how to use them as new contrast mechanism for magnetic resonance. One focus is on using parahydrogen, a spin isomer of hydrogen gas, and how to harvest its spin order to obtain signal enhanced/hyperpolarized contrast agents. 

Our current research is focused on biochemical and structural studies of how membrane molecules signal to the actin cytoskeleton through a large, five-protein complex named the WAVE Regulatory Complex (WRC). 

We investigate the neuroepigenetic mechanisms regulating synaptic plasticity in the hypothalamus, their role in maintaining body weight set-point, and how their dysregulation contributes to diet-induced obesity, weight-regain, and aging-related impairments in appetite.

Dr. Kang's research is dedicated to elucidating the molecular and immunological roles of damage-associated molecular patterns (DAMPs) and pattern recognition receptors (PRRs) in inflammatory diseases. 

Leveraging powerful new cell-based and cell-free systems, high-speed fluorescence imaging, and in vitro reconstitution using purified components to understand how cellular organelles such as peroxisomes are formed, how they acquire their unique identities and functions, and how defects in these processes cause human disease.

The Connected Aging Lab is committed to advancing brain health and emotional well-being in older adults by developing inclusive, relationship-centered interventions that bridge science, clinical care, and community.

The Mosley Lab develops and applies innovative genomic and informatics approaches to identify opportunities to use genetic background to inform clinical and public health decision-making, to identify risk factors and biomarkers of disease, and to identify and reduce heath inequities in vulnerable populations. 

Castrillion Lab's work is aimed at understanding why endometrial or uterine cancers arise and spread, with an eye on prevention, earlier and more accurate diagnosis, improved treatments, and better overall patient outcomes.

We are a group of physicists, biophysicists, cell biologists, and “computationalists” interested in the spatiotemporal organization of cell surface receptors, the mechanisms underlying it, and its consequences for cell signaling. We utilize light microscopy, particularly single-molecule and super-resolution imaging, to monitor molecular behavior in its native cellular environment, and we develop computer vision and machine learning approaches to quantitate the observed behavior and gain insight beyond what the eye can see.

Medical Artificial Intelligence and Automation

Our goal is to understand and exploit the immunogenic properties of tumor irradiation in integrating it with immunotherapy to improve cancer patient outcome.

Our mission is to innovate, develop, and apply biomedical technology to empower cancer research.

Our mission is to improve the care of breast cancer patients through cutting-edge translational research at the interface of clinical oncology, cancer biology, molecular genetics, and translational genomics.

The Moreland and Potera Labs utilize basic science approaches, in vivo models, and clinical studies to investigate cellular functions of the innate immune system.

The Davis Lab is part of the Section of Molecular Medicine in the Department of Radiation Oncology

The Brekken laboratory, located in the Hamon Center for Therapeutic Oncology Research, studies tumor-host interactions with a particular emphasis on extracellular matrix (ECM) and angiogenesis.