Publications

Featured Publications

Infectious and Inflammatory Pathways to Cough.

Naqvi KF, Mazzone SB, Shiloh MU, 2022 Sep Annu Rev Physiol

Identification of scavenger receptor B1 as the airway microfold cell receptor for Mycobacterium tuberculosis.

Khan HS, Nair VR, Ruhl CR, Alvarez-Arguedas S, Galvan Rendiz JL, Franco LH, Huang L, Shaul PW, Kim J, Xie Y, Mitchell RB, Shiloh MU, 2020 Mar Elife 9

Mycobacterium tuberculosis Sulfolipid-1 Activates Nociceptive Neurons and Induces Cough.

Ruhl CR, Pasko BL, Khan HS, Kindt LM, Stamm CE, Franco LH, Hsia CC, Zhou M, Davis CR, Qin T, Gautron L, Burton MD, Mejia GL, Naik DK, Dussor G, Price TJ, Shiloh MU, 2020 Mar Cell

Screening Mycobacterium tuberculosis Secreted Proteins Identifies Mpt64 as a Eukaryotic Membrane-Binding Bacterial Effector.

Stamm CE, Pasko BL, Chaisavaneeyakorn S, Franco LH, Nair VR, Weigele BA, Alto NM, Shiloh MU, 2019 Jun mSphere 3 4

Heme Oxygenase-1 Regulates Inflammation and Mycobacterial Survival in Human Macrophages during Mycobacterium tuberculosis Infection.

Scharn CR, Collins AC, Nair VR, Stamm CE, Marciano DK, Graviss EA, Shiloh MU 2016 Jun J. Immunol. 11 196 4641-9

Microfold Cells Actively Translocate Mycobacterium tuberculosis to Initiate Infection.

Nair VR, Franco LH, Zacharia VM, Khan HS, Stamm CE, You W, Marciano DK, Yagita H, Levine B, Shiloh MU 2016 Jul Cell Rep

Mechanisms of mycobacterial transmission: how does Mycobacterium tuberculosis enter and escape from the human host.

Shiloh MU 2016 Dec Future Microbiol 11 1503-1506

The Ubiquitin Ligase Smurf1 Functions in Selective Autophagy of Mycobacterium tuberculosis and Anti-tuberculous Host Defense.

Franco LH, Nair VR, Scharn CR, Xavier RJ, Torrealba JR, Shiloh MU, Levine B 2016 Dec Cell Host Microbe

Cyclic GMP-AMP Synthase Is an Innate Immune DNA Sensor for Mycobacterium tuberculosis.

Collins AC, Cai H, Li T, Franco LH, Li XD, Nair VR, Scharn CR, Stamm CE, Levine B, Chen ZJ, Shiloh MU 2015 Jun Cell Host Microbe

All Publications

BECN1F121A mutation increases autophagic flux in aged mice and improves aging phenotypes in an organ-dependent manner.

Sebti S, Zou Z, Shiloh MU, 2022 Aug Autophagy 1-9

Bag it, tag it: ubiquitin ligases and host resistance to Mycobacterium tuberculosis.

Campos PC, Cunha DT, Souza-Costa LP, Shiloh MU, Franco LH, 2022 Apr Trends Microbiol

EBV-driven HIV-associated diffuse large B-cell lymphoma causing profound lactic acidosis.

Prokesch BC, Shiloh MU 2014 Aug Blood 6 124 842

Mycobacterium tuberculosis MycP1 protease plays a dual role in regulation of ESX-1 secretion and virulence.

Ohol YM, Goetz DH, Chan K, Shiloh MU, Craik CS, Cox JS 2010 Mar Cell Host Microbe 3 7 210-20

To catch a killer. What can mycobacterial models teach us about Mycobacterium tuberculosis pathogenesis?

Shiloh MU, DiGiuseppe Champion PA 2010 Feb Curr. Opin. Microbiol. 1 13 86-92

A glutamate-alanine-leucine (EAL) domain protein of Salmonella controls bacterial survival in mice, antioxidant defence and killing of macrophages: role of cyclic diGMP.

Hisert KB, MacCoss M, Shiloh MU, Darwin KH, Singh S, Jones RA, Ehrt S, Zhang Z, Gaffney BL, Gandotra S, Holden DW, Murray D, Nathan C 2005 Jun Mol. Microbiol. 5 56 1234-45

Secretory leukocyte protease inhibitor, an inhibitor of neutrophil activation, is elevated in serum in human sepsis and experimental endotoxemia.

Grobmyer SR, Barie PS, Nathan CF, Fuortes M, Lin E, Lowry SF, Wright CD, Weyant MJ, Hydo L, Reeves F, Shiloh MU, Ding A 2000 May Crit. Care Med. 5 28 1276-82

Lethality of endotoxin in mice genetically deficient in the respiratory burst oxidase, inducible nitric oxide synthase, or both.

Nicholson SC, Grobmyer SR, Shiloh MU, Brause JE, Potter S, MacMicking JD, Dinauer MC, Nathan CF 1999 Apr Shock 4 11 253-8

Periplasmic superoxide dismutase protects Salmonella from products of phagocyte NADPH-oxidase and nitric oxide synthase.

De Groote MA, Ochsner UA, Shiloh MU, Nathan C, McCord JM, Dinauer MC, Libby SJ, Vazquez-Torres A, Xu Y, Fang FC 1997 Dec Proc. Natl. Acad. Sci. U.S.A. 25 94 13997-4001

A novel antioxidant gene from Mycobacterium tuberculosis.

Ehrt S, Shiloh MU, Ruan J, Choi M, Gunzburg S, Nathan C, Xie Q, Riley LW 1997 Dec J. Exp. Med. 11 186 1885-96

Evaluation of bacterial survival and phagocyte function with a fluorescence-based microplate assay.

Shiloh MU, Ruan J, Nathan C 1997 Aug Infect. Immun. 8 65 3193-8