How do cells sense metabolites to drive their growth and proliferation?  We seek to study metabolites not only as nutrients but as cellular instruction signals that dictate cell biology. 

The Sharma Lab is interested in investigating intermediary metabolism utilizing carbon-13 stable isotope tracers in conjunction with magnetic resonance spectroscopy (MRS), magnetic resonance imaging (MRI), and mass spectrometry (MS).

The Tu Lab is investigating how a variety of cellular processes and decisions are coordinated with metabolic state, and how the dysregulation of these mechanisms might be linked to disease and aging.

Our primary goal in Sieber Lab is to understand the dynamic changes in metabolic programs that support developmental and disease progression. 

Huen Lab studies how metabolic adaption promotes survival during sepsis and how the kidneys contribute to systemic metabolism during inflammation.

The Luo lab studies hypoxia stress in human cancers with a focus on epigenetic and metabolic alterations. 

We study how disseminated cancer cells survive and give rise to overt metastatic lesions.

The goal of our research is to identify key immune checkpoints of gastrointestinal disorders that could be targeted for therapeutic intervention and drug development.

Welcome to the PARK Lab.

Our lab focuses on:

1. Development of novel noninvasive imaging methods for in vivo metabolism and function
2. Identification of characteristics in metabolic diseases in vivo and ex vivo
3. Clinical translations of the metabolic imaging methods