Leveraging cutting-edge genetic and chemical screens to uncover novel and enhanced therapeutics for cancer treatment.

The Louros Lab uses a hybrid approach combining molecular biophysics, structural biology, and bioinformatics to investigate protein stability, misfolding, and aggregation, with a particular interest in neurodegenerative diseases.

We are investigating how protein homeostasis (the maturation and turnover of enzymes) interacts with lipid homeostasis.

The Rice Lab uses structure, biochemistry, reconstitution, microscopy, computer modeling, and more to study the molecular mechanisms that generate and regulate microtubule dynamics.

Our primary goal in Sieber Lab is to understand the dynamic changes in metabolic programs that support developmental and disease progression. 

The general focus of the Green Lab is to understand the molecular mechanism of the mammalian circadian clock, how it controls rhythmic biochemistry, physiology and behavior and how loss of clock function can impact health, resulting in metabolic disease, cancer and other ailments.

The Kraus Lab is interested in the basic mechanisms of nuclear signaling and gene regulation by small molecules and how these signaling pathways relate to human physiology and disease states.

Qin Lab focuses on the development of novel synthetic transformations and strategies that will allow access to bioactive, complex natural products and efficient synthesis of pharmaceuticals and their derivatives.