Orchard Lab at UT Southwestern Medical Center

We focus on neurodegenerative diseases linked to amyloid protein accumulation with the goal of developing mechanism-based diagnosis and therapy.

Dr. Gray is overseeing one of the nation’s few facilities that manufactures a special type of gene-delivering virus for patient use.

Our laboratory is interested in improving treatment for patients with glioblastoma (GBM) and other cancers. We work on understanding signal transduction pathways involved in the pathogenesis of cancer. Recent work has focused on investigating mechanisms of resistance to targeted treatment in GBM and lung cancer. We are also interested in mechanisms regulating invasion in GBM. 

Tsai Lab studies the cellular and molecular mechanisms of synapse and neural circuit development.

Pouratian Lab's primary mission is to explore basic human neuroscientific principles as well as identify brain mapping biomarkers of disease that can drive innovative approaches to restore function to patients with neurological and psychiatric diseases.