The Advanced Integrative Molecular Probe Collaboration's mission is to develop new imaging agents in a multidisciplinary approach to monitor, understand and cure disease at an early stage.

The Sharma Lab advances cardiovascular and transplant medicine through three integrated research areas:

1. Advanced metabolic imaging using hyperpolarized carbon-13 MRI and stable-isotope carbon-13 tracer methods to visualize cardiac metabolism in living tissue and patients.
2. Advanced multi-omics integrating transcriptomics and stable isotope-resolved metabolomics to map heart failure, ischemic heart disease, and donor organ biology while optimizing perfusion strategies for hearts and lungs.
3. Artificial intelligence and machine learning to develop explainable AI tools that support clinical decision-making in cardiothoracic surgery and transplantation.

Welcome to the PARK Lab.

Our lab focuses on:

1. Development of novel noninvasive imaging methods for in vivo metabolism and function
2. Identification of characteristics in metabolic diseases in vivo and ex vivo
3. Clinical translations of the metabolic imaging methods

The Davenport Lab focuses on quantitative methods for human brain imaging, primarily using MRI and Magnetoencephalography (MEG).

The Gloeggler lab is interested in spin phenomena and explores how to use them as new contrast mechanism for magnetic resonance. One focus is on using parahydrogen, a spin isomer of hydrogen gas, and how to harvest its spin order to obtain signal enhanced/hyperpolarized contrast agents. 

The Molecular Imaging and Precision Medicine Lab has four Technology Research and Development (TR&D) projects that provide a platform on which new technology is developed and disseminated. The TR&Ds are complementary and integrated and extend from the development of reagents to detect and promote an immune reactive tumor microenvironment to the synthesis of nanodrones to treat cancer and combined small-molecule diagnostic and therapeutics (theranostic agents). We focus on generation of next-generation precision platforms, tools and techniques for tackling problems at the forefront of biomedical research with a focus on those that will lead to near-term translation.

The work of the Chemical Advanced Neuroimaging Lab is focused on developing state-of-the-art proton MRS and MRSI methods and leveraging these tools to answer key clinical questions and improve the quality of neurologic care.

In our lab, we focus on the mechanisms of cerebrovascular reactivity, exploring how blood vessels in the brain respond to changes in carbon dioxide, blood pressure, and other stimuli. 

MUDIA Lab is focused on developing novel quantitative MRI techniques and analysis methods on CNS and musculoskeletal system. 

SPIL is dedicated to advancing patient care through the development and validation of cutting-edge radionuclide imaging technologies for single photon emission computed tomography (SPECT) and positron emission tomography (PET). By harnessing the power of deep learning, we aim to address key limitations of PET and SPECT imaging—such as low spatial resolution and slow data acquisition—to significantly enhance diagnostic capabilities.