Focus on Systems

Mood Disorders Research

Identifying the Areas of Greatest Impact

At the Center for Depression Research and Clinical Care, we take a multi-faceted approach to engaging with local, regional, and national communities aimed at translating our research into practice. 

To better understand the areas of greatest impact, we have identified and partnered with schools, community organizations, and healthcare systems on initiatives to improve the diagnosis and treatment of mood disorders and enhance suicide prevention efforts. 

Mood Disorders Research

The CDRC has created two community networks that provide invaluable partnership in our statewide initiatives:

Mood Disorders Network

Comprised of clinical and community members to address gaps in the screening, diagnosis, treatment, and management of depression and other mood disorders.

Risk and Resilience Network

Comprised of local schools, colleges, and youth community organizations with a focus on preventing depression and suicide through education and engagement.

Mood Disorders Research

Statewide Initiatives

The Center for Depression Research and Clinical Care is always striving to build bridges to better mental health and wellbeing for our community in Texas and beyond.

Accomplishing this means addressing the particular needs and levels of community involvement that make success possible.

Cloudbreak Initiative

A collaboration with Meadows Mental Health Policy Institute, The Cloudbreak Initiative focuses on standardizing early detection and treatment in primary care through two proven approaches.

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CTN Big S/W Node

As a key leader in the field of mood disorders, Dr. Madhukar Trivedi serves as the Principal Investigator of the National Institute on Drug Abuse (NIDA) sponsored Clinical Trials Network (CTN) Big South/West Node that researches novel interventions aimed at improving outcomes for substance use disorders.

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YAM Across Texas

Over the last 4 years, the CDRC team has reached over 14,500 youth in 29 schools (charter, public, private) with the YAM program. Due to the program’s success, the CDRC team has transitioned to training new facilitators to reach more students and create more sustainable school-based mental health programming.

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Lone Star Depression Challenge

The CDRC is participating in a collaboration with Meadows Mental Health Policy Institute, winner of the statewide Lone Star Depression Challenge, whose purpose is to scale an innovative, proven, transformative solution that builds healthier, stronger communities throughout Texas to improve the quality of life for all Texans.

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The Texas Youth Depression and Suicide Research Network (TX-YDSRN) hub is led by Dr. Madhukar Trivedi at UT Southwestern and co led by Dr. Sarah Wakefield at Texas Tech University Health Science Center. The purpose of this research network is to improve the evaluation of and response to the increasing problem of youth depression and suicide in Texas.

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Developing a Biosignature

The Texas-Resilience Against Depression program collects genetic, clinical, demographic, behavioral, and biological information from individuals at risk and those who have been diagnosed with depression or bipolar disorder. Through this 10-year program of 5,000 people, we hope to determine how best to treat and reduce the risk of mood disorders.

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T-RAD team

Mentoring the Future

The CDRC is committed to providing learning opportunities for clinicians, students, and anyone in our community interested in learning more about mental health and resilience. Through many of our programs, we are training the next generation of mental health care providers and increasing the quality of treatments to patients in North Texas.

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CRED interns with Drs. Greer and Chin Fatt

Training Youth About Mental Health

Programs available through the Risk and Resilience Network will allow adolescents to learn and develop life-long coping and resilience skills that are shown to help teens and young adults avoid high risk and self-destructive behavior that can lead to poor academic achievement, substance abuse, more severe psychiatric conditions, and even suicide.

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YAM trainer teaching in a classroom

Solving Depression, Saving Tomorrows

Be part of the great impact we're having on science and medical care across the globe.

UT Southwestern’s Treatment-Resistant Depression Clinic is a recognized center of excellence for Treatment-Resistant Mood Disorders (TRMD). These chronic or recurrent depressions comprise the most disabling forms of the disorder, and our expert clinicians are well-equipped with the latest technology and novel treatment approaches to improve the lives of patients with TRMD.