Our research program focuses on using understanding how bacteria grow in animal and human hosts as commensals and pathogens, sense and respond to host metabolites, and promote swimming motility to navigate through environments, using Campylobacter jejuni as a model system.
The foundations of our research program began by identifying and analyzing the colonization and virulence determinants of Campylobacter jejuni.
Dr. Hendrixson's research program is involved in analyzing the genetics of bacteria and the requirements of bacteria to interact with appropriate hosts. The primary research interests of the laboratory is focused on Campylobacter jejuni, a leading cause of diarrheal disease throughout the world. The Hendrixson laboratory is exploiting C. jejuni as a model for both the biogenesis and mechanics of polar flagellar motors that are required for swimming motilty and produced by many other important pathogens including Vibrio cholerae, Pseudomonas aeruginosa, and Helicobacter pylori. Dr. Hendrixson's laboratory also has a robust research program identifying requirements of C. jejuni for infection of both the human and avian host to promote disease and commensalism and how the bacterium senses and responds to in vivo conditions to modulate activities required for infection.