Kim Lab Publications

Predictors of Persistent Limp Following Proximal Femoral Varus Osteotomy for Perthes Disease

Pathogenic Gene Variants Identified in Patients Presenting with Perthes or Perthes-like Hip Disorder

Comparison of brace to observation in stable, radiological developmental dysplasia of the hip: a protocol for a global multicentre non-inferiority randomised trial

Fat Phagocytosis Promotes Anti-Inflammatory Responses of Macrophages in a Mouse Model of Osteonecrosis

Protocol for extracting and isolating porcine bone-marrow-derived macrophages from ribs

Fully automatic system to detect and segment the proximal femur in pelvic radiographic images for Legg–Calvé–Perthes disease

Obesity impairs revascularization and bone healing in a mouse model of osteonecrosis

Percutaneous transphyseal screw induces varus proximal femoral growth modulation in a growing pig model—A three-dimensional analysis

Does Screening Ultrasound Timing in Developmental Dysplasia of the Hip Need to be Adjusted for Moderate Preterm and Near-term Infants: A Prospective Study

Local BMP2 hydrogel therapy for robust bone regeneration in a porcine model of Legg-Calvé-Perthes disease

Interleukin-6 receptor blockade improves bone healing following ischemic osteonecrosis in adolescent mice

Abduction Bracing Following Anterior Open Reduction for Developmental Dysplasia of the Hip Does Not Improve Residual Dysplasia or Reduce Secondary Surgery

Patient Adherence to Wide Abduction Brace Treatment for Legg-Calvé-Perthes Disease

Reliability of the Modified Method for Sphericity Deviation Score Using Only the Involved Hip Radiographs in the Patients With Legg-Calve-Perthes Disease

The Significance of Isolated Hip Click as a Sign of DDH: Implications on Referral Guidelines

Ex vivo study of detergent-assisted intraosseous bone wash treatment of osteonecrosis

Effects of acute femoral head ischemia on the growth plate and metaphysis in a piglet model of Legg-Calvé-Perthes disease

Response to Raju et al Re: Anatomic Specific Containment in LCPD

Do Weightbearing Restrictions Cause Excess Weight Gain in Children with LEGG-Calvé-Perthes Disease?

Does brace treatment following closed reduction of developmental dysplasia of the hip improve acetabular coverage?

How are adults who had Perthes' disease functioning?

Quantitative T2 and T1ρ mapping are sensitive to ischemic injury to the epiphyseal cartilage in an in vivo piglet model of Legg-Calvé-Perthes disease

Prolonged non-weightbearing treatment decreases femoral head deformity compared to symptomatic treatment in the initial stage of Legg-Calvé-Perthes disease

What is the adult experience of Perthes’ disease? INITIAL FINDINGS FROM AN INTERNATIONAL WEB-BASED SURVEY

The Clinical Significance of Infolded Limbus on Postreduction Arthrogram in Developmental Dysplasia of the Hip

The Role of the Artery of Ligamentum Teres in Revascularization in Legg-Calve-Perthes Disease

Moderate Weightbearing Restrictions Are Associated with Worse Depressive Symptoms and Anxiety in Children Aged 5 to 7 Years with Perthes Disease

Does the Deformity Index Reliably Predict the Shape of the Femoral Head at Healing of Legg-Calvé-Perthes Disease?

T1ρ and T2 mapping detect acute ischemic injury in a piglet model of Legg–Calvé–Perthes disease

Interobserver and Intraobserver Reliability in the Salter Classification of Avascular Necrosis of the Femoral Head in Developmental Dysplasia of the Hip

Damage associated molecular patterns in necrotic femoral head inhibit osteogenesis and promote fibrogenesis of mesenchymal stem cells

Development of a murine model of ischemic osteonecrosis to study the effects of aging on bone repair

Acetabular Coverage May Affect Radiographic and Clinical Outcomes of Osteochondral Allograft Transplantation of Focal Femoral Head Lesions: A Case Series from a Single Institution

Reliability and Validity of Visual Estimation of Femoral Head Hypoperfusion on Perfusion MRI in Legg-Calve-Perthes Disease

Feasibility of Magnetic Resonance Angiography in Patients with Legg-Calvé-Perthes Disease

A rat model of ischemic osteonecrosis for investigating local therapeutics using biomaterials

Expanding the phenotypic spectrum of RPL13-related skeletal dysplasia

Minimally Invasive Necrotic Bone Washing Improves Bone Healing after Femoral Head Ischemic Osteonecrosis: An Experimental Investigation in Immature Pigs

Hip Morphology in Early-stage LCPD: Is There an Argument for Anatomic-specific Containment?

Weightbearing and Activity Restriction Treatments and Quality of Life in Patients with Perthes Disease

Diagnosis and Treatment of Femoral Head Osteonecrosis: A Protocol for Development of Evidence-Based Clinical Practice Guidelines

Diagnosis and Treatment of Femoral Head Osteonecrosis: A Protocol for Development of Evidence-Based Clinical Practice Guidelines

Silicon Oxynitrophosphide Nanoscale Coating Enhances Antioxidant Marker-Induced Angiogenesis During in vivo Cranial Bone-Defect Healing

Secondary Surgery and Residual Dysplasia Following Late Closed or Open Reduction of Developmental Dysplasia of the Hip

Reproducibility of Radiographic Measurements Made in the Active Stages of Legg-Calvé-Perthes Disease: Evaluation of a Prognostic Indicator and an Interim Outcome Measure

Anti-Interleukin-6 Therapy Decreases Hip Synovitis and Bone Resorption and Increases Bone Formation Following Ischemic Osteonecrosis of the Femoral Head

Elevation of Proinflammatory Cytokine HMGB1 in the Synovial Fluid of Patients With Legg-Calvé-Perthes Disease and Correlation With IL-6

Demographics and Clinical Presentation of Early-Stage Legg-Calvé-Perthes Disease: A Prospective, Multicenter, International Study

Demographics and Clinical Presentation of Early-Stage Legg-Calvé-Perthes Disease: A Prospective, Multicenter, International Study

Team approach: Management of osteonecrosis in children with acute lymphoblastic leukemia

Nouvelle technique mini-invasive pour éliminer le contenu de moelle osseuse nécrotique de l'os épiphysaire: étude préliminaire sur l'os cadavérique

Development of a novel minimally invasive technique to washout necrotic bone marrow content from epiphyseal bone: A preliminary cadaveric bone study

A Comparison of Transphyseal Neck-Head Tunneling and Multiple Epiphyseal Drilling on Femoral Head Healing Following Ischemic Osteonecrosis: An Experimental Investigation in Immature Pigs

The 2019 Revised Version of Association Research Circulation Osseous Staging System of Osteonecrosis of the Femoral Head

Evolution of legg-calvé-perthes disease following proximal femoral varus osteotomy performed in the avascular necrosis stage:A prospective study

Amorphous Silicon Oxynitrophosphide-Coated Implants Boost Angiogenic Activity of Endothelial Cells

Does Early Proximal Femoral Varus Osteotomy Shorten the Duration of Fragmentation in Perthes Disease? Lessons From a Prospective Multicenter Cohort

Reliability of the modified lateral pillar classification for legg calvé perthes disease performed by a large group of international paediatric orthopaedic surgeons

Validation of Pediatric Self-Report Patient-Reported Outcomes Measurement Information System (PROMIS) Measures in Different Stages of Legg-Calvé-Perthes Disease

Does participation in a multicenter study group affect physician treatment preference? A survey of participants

A Comparison of Pavlik Harness Treatment Regimens for Dislocated but Reducible (Ortolani+) Hips in Infantile Developmental Dysplasia of the Hip

Comparison of Pavlik Harness treatment regimens for reduced but dislocatable (Barlow positive) hips in infantile DDH

Analysis of Trabecular Microstructure and Vascular Distribution of Capital Femoral Epiphysis Relevant to Legg–Calve–Perthes Disease

Quantitative susceptibility mapping detects neovascularization of the epiphyseal cartilage after ischemic injury in a piglet model of legg-calvé-perthes disease

IL6 receptor blockade preserves articular cartilage and increases bone volume following ischemic osteonecrosis in immature mice

Treatment Patterns and Outcomes of Stable Hips in Infants with Ultrasonic Dysplasia

Etiologic Classification Criteria of ARCO on Femoral Head Osteonecrosis Part 1: Glucocorticoid-Associated Osteonecrosis

Etiologic Classification Criteria of ARCO on Femoral Head Osteonecrosis Part 2: Alcohol-Associated Osteonecrosis

Rapid regeneration of vascularized bone by nanofabricated amorphous silicon oxynitrophosphide (SiONP) overlays

Bio-Inspired Micropatterned Platforms Recapitulate 3D Physiological Morphologies of Bone and Dentinal Cells

Interleukin-6 deletion stimulates revascularization and new bone formation following ischemic osteonecrosis in a murine model

Ionic silicon improves endothelial cells' survival under toxic oxidative stress by overexpressing angiogenic markers and antioxidant enzymes

Quantitative MRI helps to detect hip ischemia: Preclinical model of legg-calvé-perthes disease

Ischemic femoral head osteonecrosis in a piglet model causes three dimensional decrease in acetabular coverage

Perthes disease

Long-term Outcomes of Operative and Nonoperative Treatment of Congenital Coxa Vara

In Vitro and in Vivo Characterization of Premixed PMMA-CaP Composite Bone Cements

A genome-wide transcriptomic analysis of articular cartilage during normal maturation in pigs

3D MRI Quantification of Femoral Head Deformity in Legg–Calvé–Perthes Disease

Biomechanical behavior of novel composite PMMA-CaP bone cements in an anatomically accurate cadaveric vertebroplasty model

Targeted Disruption of NF1 in Osteocytes Increases FGF23 and Osteoid With Osteomalacia-like Bone Phenotype

Material properties of bone in the femoral head treated with ibandronate and BMP-2 following ischemic osteonecrosis

Development of a Large Animal Model of Non-Weight-Bearing

Necrotic Bone Stimulates Proinflammatory Responses in Macrophages through the Activation of Toll-Like Receptor 4

Targeted disruption of BMP signaling through type IA receptor (BMPR1A) in osteocyte suppresses SOST and RANKL, leading to dramatic increase in bone mass, bone mineral density and mechanical strength

Amorphous Silica: A New Antioxidant Role for Rapid Critical-Sized Bone Defect Healing

Prevalence of Obesity in Patients with Legg-Calvé-Perthes Disease

Intraosseous Delivery of Bone Morphogenic Protein-2 Using a Self-Assembling Peptide Hydrogel

HIF-1-dependent IL-6 activation in articular chondrocytes initiating synovitis in femoral head ischemic osteonecrosis

Comprehensive genome-wide transcriptomic analysis of immature articular cartilage following ischemic osteonecrosis of the femoral head in piglets

In vivo monitoring of activated macrophages and neutrophils in response to ischemic osteonecrosis in a mouse model

Assessment of femoral head revascularization in legg-calve-perthes disease using serial perfusion MRI

Two novel high performing composite PMMA-CaP cements for vertebroplasty: An ex vivo animal study

Human periosteum cell osteogenic differentiation enhanced by ionic silicon release from porous amorphous silica fibrous scaffolds

Enhanced Interfacial Adhesion and Osteogenesis for Rapid "bone-like" Biomineralization by PECVD-Based Silicon Oxynitride Overlays

Legg-Calvé-Perthes disease produces chronic hip synovitis and elevation of interleukin-6 in the synovial fluid

Correction: Decreasing NF-κB expression enhances odontoblastic differentiation and collagen expression in dental pulp stem cells exposed to inflammatory cytokines

Interobserver and intraobserver reliability of the modified waldenström classification system for staging of legg-calvé-perthes disease

Bone Apatite Composition of Necrotic Trabecular Bone in the Femoral Head of Immature Piglets

Quantitative assessment of synovitis in Legg-Calvé-Perthes disease using gadolinium-enhanced MRI

Development of a Mouse Model of Ischemic Osteonecrosis

Decreasing NF-κB expression enhances odontoblastic differentiation and collagen expression in dental pulp stem cells exposed to inflammatory cytokines

Physeal injuries and growth disturbances

Neurofibromin deficiency-associated transcriptional dysregulation suggests a novel therapy for tibial pseudoarthrosis in NF1

Regulation of bone and skeletal development by the SHP-2 protein tyrosine phosphatase

Physeal injuries and growth disturbances

Local administration of bone morphogenetic protein-2 and bisphosphonate during non-weight-bearing treatment of ischemic osteonecrosis of the femoral head: An experimental investigation in immature pigs

Physeal injuries and growth disturbances

Perfusion MRI in early stage of Legg-Calvé-Perthes disease to predict lateral pillar involvement: A preliminary study

What is the usefulness of the fragmentation pattern of the femoral head in managing Legg-Calvé-Perthes disease?

The impact of large-scale genomic methods in orthopaedic disorders: Insights from genome-wide association studies

Targeted disruption of Shp2 in chondrocytes leads to metachondromatosis with multiple cartilaginous protrusions

Legg-Calvé-perthes disease: Pathology, pathophysiology, and pathogenesis of deformity

Legg-calvé-perthes disease: Treatments

Corticosteroid-associated osteonecrosis in children

Legg-calvé-perthes disease: Diagnosis, imaging, and classifications

Developing medical therapy for legg-calvé- perthes’ disease

Pecvd SiOx accelerates hydroxyapatite surface formation for enhanced early osteogenic differentiation

Feasibility and safety of perfusion MRI for Legg-Calvé-Perthes disease

Whole-exome sequencing: Discovering genetic causes of orthopaedic disorders

Female patients with late-onset Legg-Calvé-Perthes disease are frequently gymnasts: Is there a mechanical etiology for this subset of patients?

Induction of SHP2 deficiency in chondrocytes causes severe scoliosis and kyphosis in mice

MR perfusion index as a quantitative method of evaluating epiphyseal perfusion in legg-calve-perthes disease and correlation with short-term radiographic outcome: A preliminary study

A comparison of non-contrast and contrast-enhanced MRI in the initial stage of Legg-Calvé-Perthes disease

High-concentration of BMP2 reduces cell proliferation and increases apoptosis via DKK1 and SOST in human primary periosteal cells

Acute BMP2 upregulation following induction of ischemic osteonecrosis in immature femoral head

Lactoferrin activates BMP7 gene expression through the mitogen-activated protein kinase ERK pathway in articular cartilage

Microcrack density and nanomechanical properties in the subchondral region of the immature piglet femoral head following ischemic osteonecrosis

Citrate-based biodegradable injectable hydrogel composites for orthopedic applications

Effects of non-weight-bearing on the immature femoral head following ischemic osteonecrosis: An experimental investigation in immature pigs

Evidence for using bisphosphonate to treat Legg-Calvé-Perthes disease hip

Pathophysiology and new strategies for the treatment of Legg-Calvé-Perthes disease

Detecting a disruption of blood flow to the femoral head after ischemic injury using 4 different techniques: A preliminary study

Regulation of VEGF expression by HIF-1α in the femoral head cartilage following ischemia osteonecrosis

Potential for bisphosphonate treatment in Legg-Calve-Perthes disease

Legg-Calve-Perthes disease: Etiology, pathogenesis, and biology

Subchondral fracture after ischemic osteonecrosis of the immature femoral head in piglet model

Pathophysiology, Classifications, and Natural History of Perthes Disease

Future Biologic Treatments for Perthes Disease

Local administration of ibandronate and bone morphogenetic protein-2 after ischemic osteonecrosis of the immature femoral head: A combined therapy that stimulates bone formation and decreases femoral head deformity

Hypoxia-inducible factor-1 is a positive regulator of Sox9 activity in femoral head osteonecrosis

Childhood femoral head osteonecrosis

How much varus is optimal with proximal femoral osteotomy to preserve the femoral head in Legg-Calvé-Perthes disease?

Bisphosphonate-modified gold nanoparticles: A useful vehicle to study the treatment of osteonecrosis of the femoral head

Citric acid-derived in situ crosslinkable biodegradable polymers for cell delivery

Legg-Calvé-Perthes disease

Evaluation of a pig femoral head osteonecrosis model

Increased matrix mineralization in the immature femoral head following ischemic osteonecrosis

Hypoxia and HIF-1α expression in the epiphyseal cartilage following ischemic injury to the immature femoral head

Effects of disruption of epiphyseal vasculature on the proximal femoral growth plate

Biomechanical properties of bone and cartilage in growing femoral head following ischemic osteonecrosis

Erratum: Retention, distribution, and effects of intraosseously administered ibandronate in the infarcted femoral head (Journal of Bone and Mineral Research (2007) 22, 1 (93-100))

Ischaemic injury to femoral head induces apoptotic and oncotic cell death

Retention, distribution, and effects of intraosseously administered ibandronate in the infarcted femoral head

Introduction to osteonecrosis of the femoral head (OFH) and osteonecrosis of the jaw (ONJ).

Osteonecrosis and osteonecrosis of the jaw (ONJ).

RANKL inhibition: A novel strategy to decrease femoral head deformity after ischemic osteonecrosis

Local bioavailability and distribution of systemically (parenterally) administered ibandronate in the infarcted femoral head

Femoral neck fracture in a child with autosomal-dominant osteopetrosis: Failure of spica cast treatment and successful outcome by internal fixation

Regenaration of the proximal tibial epiphysis after infantile osteomyelitis. Report of three cases with an eight- to 22-year follow-up

Ibandronate for prevention of femoral head deformity after ischemic necrosis of the capital femoral epiphysis in immature pigs

Increased VEGF expression in the epiphyseal cartilage after ischemic necrosis of the capital femoral epiphysis

Pathogenesis of Metaphyseal Radiolucent Changes Following Ischemic Necrosis of the Capital Femoral Epiphysis in Immature Pigs: A Preliminary Report

Indentation properties of growing femoral head following ischemic necrosis

The effects of limb lengthening on growth

Nonunion as a complication of an open reduction of a distal radial fracture in a healthy child: A case report

Development of flattening and apparent fragmentation following ischemic necrosis of the capital femoral epiphysis in a piglet model

Histopathologic changes in growth-plate cartilage following ischemic necrosis of the capital femoral epiphysis: An experimental investigation in immature pigs

Porcine factor V: cDNA cloning, gene mapping, three-dimensional protein modeling of membrane binding sites and comparative anatomy of domains

A shortened course of parenteral antibiotic therapy in the management of acute septic arthritis of the hip

Pelvic obliquity after fusion of the spine in Duchenne muscular dystrophy

MRI of the cartilaginous epiphysis of the femoral head in the piglet hip after ischemic damage

The effects of postoperative continuous passive motion on peripheral nerve repair and regeneration: An experimental investigation in rabbits

Ultrasound biomicroscopy and magnetic resonance imaging of reconstituted articular cartilage

Traumatic heterotopic bone formation in the quadriceps muscle. No progression by continuous passive motion in rabbits

High-resolution magnetic resonance imaging of normal porcine cartilaginous epiphyseal maturation

Imaging of immature articular cartilage using ultrasound backscatter microscopy at 50 MHz

Effects of continuous passive motion and immobilization on synovitis and cartilage degradation in antigen induced arthritis

Ultrasound backscatter microscopy of articular cartilage in vitro

Biological resurfacing of full-thickness defects in patellar articular cartilage of the rabbit: Investigation of autogenous periosteal grafts subjected to continuous passive motion

The potential for regeneration of articular cartilage in defects created by chondral shaving and subchondral abrasion. An experimental investigation in rabbits