Kim Lab Publications

Do Weightbearing Restrictions Cause Excess Weight Gain in Children With LEGG-Calve-Perthes Disease?

Quantitative T2 and T1? mapping are sensitive to ischemic injury to the epiphyseal cartilage in an in vivo piglet model of Legg-Calve-Perthes disease.

Interobserver and Intraobserver Reliability in the Salter Classification of Avascular Necrosis of the Femoral Head in Developmental Dysplasia of the Hip.

The Role of the Artery of Ligamentum Teres in Revascularization in Legg-Calve-Perthes Disease.

The Clinical Significance of Infolded Limbus on Postreduction Arthrogram in Developmental Dysplasia of the Hip.

Does the Deformity Index Reliably Predict the Shape of the Femoral Head at Healing of Legg-Calve-Perthes Disease?

How are adults who had Perthes' disease functioning? : results of over 900 participants from an international web-based survey.

Ex vivo study of detergent-assisted intraosseous bone wash treatment of osteonecrosis.

Damage Associated Molecular Patterns in Necrotic Femoral Head Inhibit Osteogenesis and Promote Fibrogenesis of Mesenchymal Stem Cells.

Moderate Weightbearing Restrictions Are Associated with Worse Depressive Symptoms and Anxiety in Children Aged 5 to 7 Years with Perthes Disease.

Acetabular Coverage May Affect Radiographic and Clinical Outcomes of Osteochondral Allograft Transplantation of Focal Femoral Head Lesions: A Case Series From a Single Institution.

Prolonged non-weightbearing treatment decreases femoral head deformity compared to symptomatic treatment in the initial stage of Legg-Calve-Perthes disease.

T1? and T2 mapping detect acute ischemic injury in a piglet model of Legg-Calve-Perthes disease.

Minimally Invasive Necrotic Bone Washing Improves Bone Healing After Femoral Head Ischemic Osteonecrosis: An Experimental Investigation in Immature Pigs.

Hip Morphology in Early-stage LCPD: Is There an Argument for Anatomic-specific Containment?

A rat model of ischemic osteonecrosis for investigating local therapeutics using biomaterials.

Development of a murine model of ischemic osteonecrosis to study the effects of aging on bone repair.

Reliability and Validity of Visual Estimation of Femoral Head Hypoperfusion on Perfusion MRI in Legg-Calve-Perthes Disease.

Feasibility of Magnetic Resonance Angiography in Patients With Legg-Calve-Perthes Disease.

Diagnosis and Treatment of Femoral Head Osteonecrosis: A Protocol for Development of Evidence-Based Clinical Practice Guidelines.

Anti-Interleukin-6 Therapy Decreases Hip Synovitis and Bone Resorption and Increases Bone Formation Following Ischemic Osteonecrosis of the Femoral Head.

Expanding the phenotypic spectrum of RPL13-related skeletal dysplasia.

Reproducibility of Radiographic Measurements Made in the Active Stages of Legg-Calve-Perthes Disease: Evaluation of a Prognostic Indicator and an Interim Outcome Measure.

Team approach: Management of osteonecrosis in children with acute lymphoblastic leukemia.

Development of a novel minimally invasive technique to washout necrotic bone marrow content from epiphyseal bone: A preliminary cadaveric bone study.

Secondary Surgery and Residual Dysplasia Following Late Closed or Open Reduction of Developmental Dysplasia of the Hip.

Weightbearing and Activity Restriction Treatments and Quality of Life in Patients with Perthes Disease.

Demographics and Clinical Presentation of Early-Stage Legg-Calve-Perthes Disease: A Prospective, Multicenter, International Study.

A Comparison of Transphyseal Neck-Head Tunneling and Multiple Epiphyseal Drilling on Femoral Head Healing Following Ischemic Osteonecrosis: An Experimental Investigation in Immature Pigs.

Does Early Proximal Femoral Varus Osteotomy Shorten the Duration of Fragmentation in Perthes Disease? Lessons From a Prospective Multicenter Cohort.

Amorphous Silicon Oxynitrophosphide-Coated Implants Boost Angiogenic Activity of Endothelial Cells.

A Comparison of Pavlik Harness Treatment Regimens for Dislocated But Reducible (Ortolani+) Hips in Infantile Developmental Dysplasia of the Hip.

The 2019 Revised Version of Association Research Circulation Osseous Staging System of Osteonecrosis of the Femoral Head.

Rapid Regeneration of Vascularized Bone by Nanofabricated Amorphous Silicon Oxynitrophosphide (SiONP) Overlays.

Validation of Pediatric Self-Report Patient-Reported Outcomes Measurement Information System (PROMIS) Measures in Different Stages of Legg-Calve-Perthes Disease.

IL6 receptor blockade preserves articular cartilage and increases bone volume following ischemic osteonecrosis in immature mice.

Analysis of Trabecular Microstructure and Vascular Distribution of Capital Femoral Epiphysis Relevant to Legg-Calve-Perthes Disease.

Treatment Patterns and Outcomes of Stable Hips in Infants With Ultrasonic Dysplasia.

Etiologic Classification Criteria of ARCO on Femoral Head Osteonecrosis Part 2: Alcohol-Associated Osteonecrosis.

Etiologic Classification Criteria of ARCO on Femoral Head Osteonecrosis Part 1: Glucocorticoid-Associated Osteonecrosis.

Quantitative MRI Helps to Detect Hip Ischemia: Preclinical Model of Legg-Calve-Perthes Disease.

Ionic Silicon Improves Endothelial Cells' Survival Under Toxic Oxidative Stress by Overexpressing Angiogenic Markers and Antioxidant Enzymes.

Quantitative susceptibility mapping detects neovascularization of the epiphyseal cartilage after ischemic injury in a piglet model of legg-calve-perthes disease.

Bio-Inspired Micropatterned Platforms Recapitulate 3D Physiological Morphologies of Bone and Dentinal Cells.

Interleukin-6 deletion stimulates revascularization and new bone formation following ischemic osteonecrosis in a murine model.

A genome-wide transcriptomic analysis of articular cartilage during normal maturation in pigs.

Ischemic Femoral Head Osteonecrosis in a Piglet Model Causes Three Dimensional Decrease in Acetabular Coverage.

In Vitro and In Vivo Characterization of Premixed PMMA-CaP Composite Bone Cements.

Targeted disruption of NF1 in osteocyte increases FGF23 and osteoid with osteomalacia-like bone phenotype.

Necrotic Bone Stimulates Proinflammatory Responses in Macrophages through the Activation of Toll-Like Receptor 4.

Biomechanical behavior of novel composite PMMA-CaP bone cements in an anatomically accurate cadaveric vertebroplasty model.

3D MRI quantification of femoral head deformity in legg-calve-perthes disease.

Assessment of Femoral Head Revascularization in Legg-Calve-Perthes Disease Using Serial Perfusion MRI.

Intraosseous Delivery of Bone Morphogenic Protein-2 Using a Self-Assembling Peptide Hydrogel.

Long-term Outcomes of Operative and Nonoperative Treatment of Congenital Coxa Vara.

Prevalence of Obesity in Patients With Legg-Calve-Perthes Disease.

Targeted disruption of BMP signaling through type IA receptor (BMPR1A) in osteocyte suppresses SOST and RANKL, leading to dramatic increase in bone mass, bone mineral density and mechanical strength.

Amorphous Silica: A New Antioxidant Role for Rapid Critical-Sized Bone Defect Healing.

HIF-1-Dependent IL-6 Activation in Articular Chondrocytes Initiating Synovitis in Femoral Head Ischemic Osteonecrosis.

Material properties of bone in the femoral head treated with ibandronate and BMP-2 following ischemic osteonecrosis.

Comprehensive Genome-Wide Transcriptomic Analysis of Immature Articular Cartilage following Ischemic Osteonecrosis of the Femoral Head in Piglets.

In vivo monitoring of activated macrophages and neutrophils in response to ischemic osteonecrosis in a mouse model.

Two novel high performing composite PMMA-CaP cements for vertebroplasty: An ex vivo animal study.

Enhanced Interfacial Adhesion and Osteogenesis for Rapid "Bone-like" Biomineralization by PECVD-based Silicon Oxynitride Overlays.

Human periosteum cell osteogenic differentiation enhanced by ionic silicon release from porous amorphous silica fibrous scaffolds.

Legg-Calve-Perthes Disease Produces Chronic Hip Synovitis and Elevation of Interleukin-6 in the Synovial Fluid.

Development of a Mouse Model of Ischemic Osteonecrosis.

Bone Apatite Composition of Necrotic Trabecular Bone in the Femoral Head of Immature Piglets.

Interobserver and intraobserver reliability of the modified waldenstrom classification system for staging of legg-calve-perthes disease.

Decreasing NF-?B Expression Enhances Odontoblastic Differentiation and Collagen Expression in Dental Pulp Stem Cells Exposed to Inflammatory Cytokines.

Local administration of bone morphogenetic protein-2 and bisphosphonate during non-weight-bearing treatment of ischemic osteonecrosis of the femoral head: an experimental investigation in immature pigs.

Quantitative assessment of synovitis in Legg-Calve-Perthes disease using gadolinium-enhanced MRI.

The impact of large-scale genomic methods in orthopaedic disorders: insights from genome-wide association studies.

Neurofibromin Deficiency-Associated Transcriptional Dysregulation Suggests a Novel Therapy for Tibial Pseudoarthrosis in NF1.

What is the usefulness of the fragmentation pattern of the femoral head in managing legg-calve-perthes disease?

Perfusion MRI in Early Stage of Legg-Calve-Perthes Disease to Predict Lateral Pillar Involvement: A Preliminary Study.

Feasibility and Safety of Perfusion MRI for Legg-Calve-Perthes Disease.

Regulation of bone and skeletal development by the SHP-2 protein tyrosine phosphatase.

MR perfusion index as a quantitative method of evaluating epiphyseal perfusion in Legg-Calve-Perthes disease and correlation with short-term radiographic outcome: a preliminary study.

Induction of SHP2 deficiency in chondrocytes causes severe scoliosis and kyphosis in mice.

A comparison of non-contrast and contrast-enhanced MRI in the initial stage of Legg-Calve-Perthes disease.

Acute BMP2 upregulation following induction of ischemic osteonecrosis in immature femoral head.

High-concentration of BMP2 reduces cell proliferation and increases apoptosis via DKK1 and SOST in human primary periosteal cells.

Microcrack density and nanomechanical properties in the subchondral region of the immature piglet femoral head following ischemic osteonecrosis.

Lactoferrin activates BMP7 gene expression through the mitogen-activated protein kinase ERK pathway in articular cartilage.

Whole-exome sequencing: discovering genetic causes of orthopaedic disorders.

Female patients with late-onset legg-calve-perthes disease are frequently gymnasts: is there a mechanical etiology for this subset of patients?

Targeted disruption of Shp2 in chondrocytes leads to metachondromatosis with multiple cartilaginous protrusions.

Detecting a disruption of blood flow to the femoral head after ischemic injury using 4 different techniques: a preliminary study.

Effects of non-weight-bearing on the immature femoral head following ischemic osteonecrosis: an experimental investigation in immature pigs.

Pathophysiology and new strategies for the treatment of Legg-Calve-Perthes disease.

Regulation of VEGF expression by HIF-1a in the femoral head cartilage following ischemia osteonecrosis.

Potential for bisphosphonate treatment in Legg-Calve-Perthes disease.

Legg-Calve-Perthes disease: etiology, pathogenesis, and biology.

Local administration of ibandronate and bone morphogenetic protein-2 after ischemic osteonecrosis of the immature femoral head: a combined therapy that stimulates bone formation and decreases femoral head deformity.

Hypoxia-inducible factor-1 is a positive regulator of Sox9 activity in femoral head osteonecrosis.

Subchondral fracture after ischemic osteonecrosis of the immature femoral head in piglet model.

Future biologic treatments for perthes disease.

Pathophysiology, classifications, and natural history of perthes disease.

Bisphosphonate-modified gold nanoparticles: a useful vehicle to study the treatment of osteonecrosis of the femoral head.

How much varus is optimal with proximal femoral osteotomy to preserve the femoral head in Legg-Calve-Perthes disease?

Increased matrix mineralization in the immature femoral head following ischemic osteonecrosis.

Citric acid-derived in situ crosslinkable biodegradable polymers for cell delivery.

Effects of disruption of epiphyseal vasculature on the proximal femoral growth plate.

Hypoxia and HIF-1alpha expression in the epiphyseal cartilage following ischemic injury to the immature femoral head.

Biomechanical properties of bone and cartilage in growing femoral head following ischemic osteonecrosis.

Retention, distribution, and effects of intraosseously administered ibandronate in the infarcted femoral head.

Ischaemic injury to femoral head induces apoptotic and oncotic cell death.

Introduction to osteonecrosis of the femoral head (OFH) and osteonecrosis of the jaw (ONJ).

Osteonecrosis and osteonecrosis of the jaw (ONJ).

Local bioavailability and distribution of systemically (parenterally) administered ibandronate in the infarcted femoral head.

RANKL inhibition: a novel strategy to decrease femoral head deformity after ischemic osteonecrosis.

Ibandronate for prevention of femoral head deformity after ischemic necrosis of the capital femoral epiphysis in immature pigs.

Regeneration of the proximal tibial epiphysis after infantile osteomyelitis: report of three cases with an eight- to 22-year follow-up.

Femoral neck fracture in a child with autosomal-dominant osteopetrosis: failure of spica cast treatment and successful outcome by internal fixation.

Indentation properties of growing femoral head following ischemic necrosis.

Pathogenesis of metaphyseal radiolucent changes following ischemic necrosis of the capital femoral epiphysis in immature pigs. A preliminary report.

Increased VEGF expression in the epiphyseal cartilage after ischemic necrosis of the capital femoral epiphysis.

The effects of limb lengthening on growth.

Nonunion as a complication of an open reduction of a distal radial fracture in a healthy child: a case report.

Development of flattening and apparent fragmentation following ischemic necrosis of the capital femoral epiphysis in a piglet model.

Histopathologic changes in growth-plate cartilage following ischemic necrosis of the capital femoral epiphysis. An experimental investigation in immature pigs.

Porcine factor V: cDNA cloning, gene mapping, three-dimensional protein modeling of membrane binding sites and comparative anatomy of domains.

A shortened course of parenteral antibiotic therapy in the management of acute septic arthritis of the hip.

Pelvic obliquity after fusion of the spine in Duchenne muscular dystrophy.

The effects of postoperative continuous passive motion on peripheral nerve repair and regeneration. An experimental investigation in rabbits.

MRI of the cartilaginous epiphysis of the femoral head in the piglet hip after ischemic damage.

Traumatic heterotopic bone formation in the quadriceps muscle. No progression by continuous passive motion in rabbits.

High-resolution magnetic resonance imaging of normal porcine cartilaginous epiphyseal maturation.

Effects of continuous passive motion and immobilization on synovitis and cartilage degradation in antigen induced arthritis.

Imaging of immature articular cartilage using ultrasound backscatter microscopy at 50 MHz.

Biological resurfacing of full-thickness defects in patellar articular cartilage of the rabbit. Investigation of autogenous periosteal grafts subjected to continuous passive motion.