The Osborne Lab focuses on how regulation of miRNA and mRNA controls the branching of developing cells, and how disregulation of these pathways contributes to aggressive tumor behavior.

Huen Lab studies how metabolic adaption promotes survival during sepsis and how the kidneys contribute to systemic metabolism during inflammation.

The Tagliabracci Lab studies the phosphorylation of extracellular proteins by a novel family of secreted kinases. This kinase family is so different from canonical kinases that it was not included as a branch on the human kinome tree.

The main focus of the Minna Lab is translational (“bench to bedside”) cancer research aimed at developing new ways to diagnose, prevent, and treat lung cancer based on a detailed understanding of the molecular pathogenesis of lung cancer.

The Nicastro Lab studies 3D ultra-structures and cell biological functions of macro-molecular complexes inside cells.

The Mangelsdorf/Kliewer Lab studies two signal transduction pathways that offer new therapeutic potential for treating diseases such as diabetes, obesity, cancer, and parasitism.

Henne lab is interested in how cells spatially organize their metabolism to adapt to a constantly changing environment.

The Liou Lab seeks to understand the principles underlying communication between organelles within mammalian cells.

The Davis Lab is part of the Section of Molecular Medicine in the Department of Radiation Oncology

Our laboratory is interested in investigating the molecular mechanisms of selenoproteins in health and disease.