We unite researchers with diverse expertise in computational modeling, biochemical reconstitution, structural analysis of polymers, and cell biology to focus on three distinct condensates that are important for genome homeostasis.
Our laboratory is interested in understanding how the ubiquitin-mediated protein degradation regulates gene expression and how failure of these pathways contributes to developmental disorders and diseases, such as neurodegeneration and cancer.
Dr. Prinz's research is focused on the tiny organelles within cells that do the cell’s work, much like the organs in a human body. He is best known for studies into the exchange of fats (also called lipids) between organelles at so-called membrane contact sites where organelles come in close contact within a cell.
The main focus in our laboratory is the identification and physiological characterization of adipocyte-specific gene products and the elucidation of pathways that are an integral part of the complex set of reactions that drive adipogenesis.
The N-LAB's mission is to develop novel neuroimaging and neuroengineering methods to integrate molecular and system neuroscience and solve brain science problems.
We study the physical mechanisms that underlie animal development.
Our goal is to employ cryo-EM to determine high resolution structures of important membrane protein complexes involved in cellular signaling, including cellular receptors and ion channels. We also combine structural approaches with functional studies to reveal the structure-function relationships of these membrane proteins.
The Marciano laboratory investigates fundamental aspects of kidney development and regeneration, in both health and disease.
The Danuser lab develops computer vision methods and mathematical models in combination with live cell imaging approaches to unveil non-genetic mechanisms of cancer metastasis and drug resistance.
Specialty areas: Computer Vision, Computational Biology, Live Cell Imaging
Michaely Lab focuses on the function of the proteins that control plasma membrane function. We have on-going projects investigating ARH/LDLR endocytosis and caveolae signal transduction.
