The Ishii Laboratory is interested in understanding the bidirectional relationship between brain function and systemic metabolism with an emphasis on metabolic deficits in Alzheimer’s disease and how it differs from normal aging. Our laboratory focuses on generating hypotheses derived from open questions in clinical neurology and neuroendocrinology, testing these hypotheses using molecular genetics and neuroscience techniques in the laboratory, and whenever possible verifying these findings in clinically relevant human research studies. 

The Noch Lab is a basic and translational research laboratory focused on identifying novel strategies to target metabolic vulnerabilities in glioma.

The Stopschinski lab investigates molecular and cellular mechanisms that drive neurodegeneration in Alzheimer’s Disease and other tauopathies with the goal to find new diagnostic and therapeutic approaches for these conditions.

The Ding lab is led by Dr. Kan Ding, an Associate Professor and practicing neurologist who specializes in epilepsy. The lab concentrates on neurocritical care and post-traumatic epilepsy, with the goal of advancing strategies for diagnosis, treatment, and rehabilitation to improve care for those with epilepsy. 

We aim to elucidate the role of the innate immune system in damage and repair following ischemic and hemorrhagic insults to the brain. We are specifically focused on innate immune drivers of secondary injury following aneurysmal subarachnoid hemorrhage and the immune response triggered by acute intracranial pressure spikes during aneurysm rupture. We also look into promoting recovery after ischemic stroke by reprogramming microglia and peripheral myeloid cells to drive repair. In addition, we are pursuing the development of therapeutics for intraarterial immunomodulation for chronic subdural hemorrhage.

The Sguigna lab investigates the visual system in multiple sclerosis, and other neurological conditions, with the intent of leveraging technologies to further science both diagnostically and therapeutically. 

Heart-Brain Connection Program

The Monson Lab is dedicated to understanding how B cells and T cells impact pathology of disease in the central nervous system.

Our mission is to better unravel the causes and mechanisms underlying tremor disorders as well as understand the clinical features of these disorders.

We are interested in the circuit mechanisms of how the cerebellum helps the brain to work better in health and disease.