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Deja Lab is dedicated to advancing the field of metabolomics and fluxomics in metabolic disease research.

Our laboratory’s focus is to understand the intrinsic roles of lysosomes and their regulatory functions in cellular and organismal homeostasis, with the ultimate goal of identifying novel therapeutic targets for a wide range of disease conditions.

Dr. Zhu has investigated disease mechanisms and attempted to develop novel therapeutic strategies for tumor suppressor gene (TSG), syndrome-associated tumors in the nervous system, and neuropsychiatric disorders.

The Ruan Lab focuses its research on developing statistical methods and computational algorithms for multi-omics data with applications in complex human diseases.

The Liang lab's research focuses on delineating the pathophysiological mechanisms underlying chronic liver disease.

The Calvier Lab's research focuses on endothelial modulation as a therapeutic approach to inflammatory diseases.

We aim to characterize the ways in which reward systems vary from individual to individual and understand how this variation determines propensity for depression and addiction-like behavior.

The Tatara Laboratory applies engineering technologies to study and treat infectious diseases. We are particularly engaged in device-related infection, orthopedic immunology, and pathogen virulence on biomaterial surfaces. 

Wang Lab focuses on how genetic factor and transcription regulation function in skeletal disease and bone cancer.

Our laboratory is interested in investigating the molecular mechanisms of selenoproteins in health and disease.

The BraNiC lab is dedicated to developing advanced methods for assessing the potential for brain function recovery after severe brain injuries.

The Leavey Lab focuses on clinical and translational trials in pediatric sarcoma.

Our lab specializes in developing advanced algorithms for medical image analysis and pioneering artificial intelligence (AI) models tailored for medical research. These innovative tools are essential in improving diagnostic accuracy and assessing surgical outcomes with greater precision. We leverage a comprehensive approach, integrating both radiological and non-radiological imaging techniques to deliver thorough and accurate analyses.

In our lab, we focus on the mechanisms of cerebrovascular reactivity, exploring how blood vessels in the brain respond to changes in carbon dioxide, blood pressure, and other stimuli. 

The work of the CHemical Advanced Neuroimaging lab is focused on developing state-of-the-art proton MRS and MRSI methods and leveraging these tools to answer key clinical questions and improve the quality of neurologic care.

Our lab specializes in clinical and research informatics, with a diverse portfolio of projects that leverage electronic health record (EHR) data and multimodal research data to enhance clinical care and advance research in the neurosciences.

The Yan Lab studies molecular mechanisms of innate immunity in infection, autoimmune diseases, cancer immunology and neurodegenative diseases.

Engineered hydrogel biomaterials to improve tissue regeneration and disease modelling

Dr. Coughlin's Brain Health Program research focuses on molecular neuroimaging techniques, particularly the use of novel radiotracers with positron emission tomography (PET). Her team aims to inform the molecular understanding of neuropsychiatric conditions, and identify novel, precision therapies guided by imaging results. 

The Bezerra Lab current studies investigate how developmental defects increase the susceptibility of the biliary epithelium to infectious and toxic insults.