The Louros Lab uses a hybrid approach combining molecular biophysics, structural biology, and bioinformatics to investigate protein stability, misfolding, and aggregation, with a particular interest in neurodegenerative diseases.

The Shahmoradian lab investigates the roles of domain-specific neuronal proteins using advanced cryo-imaging techniques to understand their impact on cellular dynamics and neurological health.

Xin Liu Lab is interested in understanding the regulation of transcription and chromatin dynamics underlying many fundamental biological processes including differentiation, development, and oncogenesis.

We focus on the discovery of targeted therapies for major drivers of cancer using protein chemistry, enzymology, structural biology, informatics and cell biology. Some of our favorite targets are RAS and kinase proteins.

The Zhang lab studies intra- and inter-molecular interactions to understand how signaling proteins are regulated, using biochemistry, X-ray crystallography, cryo-EM and cell biology.

Saelices Lab employs crystallography and cryo-EM to study amyloid deposition and design anti-amyloid tools.

The Rosen Lab seeks to understand the formation, regulation, functions and internal structures of membraneless cellular compartments termed biomolecular condensates.