Research lab at UT Southwestern for Mohan Krishnan, Ph.D.

The Moe Lab specializes in translational pathophysiology that spans from individual molecules, in vitro cell models, in vivo animal models, to metabolic human studies. 

We are dedicated to uncovering how G protein–coupled receptors (GPCRs) regulate metabolism and contribute to health and disease. Our research aims to translate these discoveries into new insights and therapeutic strategies.

Using patient-specific stem cells, tissue engineering, and omics technologies to develop precision medicine for cardiovascular disease.

research lab at UT Southwestern for Yun Wei, Ph.D.

In the Suleiman Lab, we focus on studying the podocyte biology, specifically the actin dynamics and cytoskeleton. Our research includes examining the balance of Rac and RhoA, two members of the Rho small GTPases, in both healthy and diseased kidneys. 

The Wang Lab investigates the roles of genetic factors and transcriptional regulation in skeletal diseases and bone cancer.

We unite researchers with diverse expertise in computational modeling, biochemical reconstitution, structural analysis of polymers, and cell biology to focus on three distinct condensates that are important for genome homeostasis.

Our laboratory is interested in understanding how the ubiquitin-mediated protein degradation regulates gene expression and how failure of these pathways contributes to developmental disorders and diseases, such as neurodegeneration and cancer.

The Nanes Lab investigates how the keratin intermediate filament cytoskeleton organizes cell regulatory circuits during skin development, wound healing, and cancer.