Displaying 241 - 260 of 2213
A major focus of the Horton lab is to determine how these transcriptional regulators contribute to the development of steatosis in various disease processes such as diabetes, obesity, and beta-oxidation defects. A second area of investigation centers on determining the function of PCSK9, a protein that is involved in determining plasma LDL cholesterol levels through its ability to post-transcriptionally regulate the expression of the LDL receptor in liver.
We are interested in how membrane cholesterol controls diverse cellular signaling pathways to ensure lipid homeostasis, enable cell growth, and protect against infections.
The Gospocic group studies how epigenetic pathways and gene expression regulate brain plasticity in the context of social behavior and aging by working with a unique ant species Harpegnathos saltator. We take a multidisciplinary approach and combine functional genomics, biochemistry, and behavioral assays in H. saltator, as well as the conventional Drosophila and mouse models to expedite genetic screening and provide evolutionary context to identified epigenetic pathways.
Specialty Areas: epigenetics, chromatin biology, gene regulation, social behavior, aging, neurodegeneration
Our laboratory aims to understand the role of metabolic adaptive mechanisms in cancer progression.
The Ye Lab is broadly interested in lipid-mediated signaling reactions.
Through our expertise, our expert team is leading the charge to develop more effective alternate therapies for urinary tract infections.
The UT Larynx Lab is a collaboration between The University of Texas at Dallas and UT Southwestern. Our research focuses on the role of the larynx in vocal production and sensorimotor voice and breathing disorders.
The Henning lab develops novel ultra-high field MRI and metabolic MRI methodology for human application and translates it to neuroscientific, physiological and clinical trials in brain, spine, heart and muscle disorders.
We aim to elucidate the role of the innate immune system in damage and repair following ischemic and hemorrhagic insults to the brain. We are specifically focused on innate immune drivers of secondary injury following aneurysmal subarachnoid hemorrhage and the immune response triggered by acute intracranial pressure spikes during aneurysm rupture. We also look into promoting recovery after ischemic stroke by reprogramming microglia and peripheral myeloid cells to drive repair. In addition, we are pursuing the development of therapeutics for intraarterial immunomodulation for chronic subdural hemorrhage.
Dr. Park’s research focuses on the visual system and how the projection neurons in the retina, the retinal ganglion cell axons, find their targets and form synapses in the brain. He is investigating two key areas: 1) cellular and molecular mechanisms underlying the death of neurons and lack of regeneration in the central nervous system after injury and in degenerative diseases like glaucoma and 2) mechanisms by which neurons form proper connections with each other.
We study how disseminated cancer cells survive and give rise to overt metastatic lesions.
Dr. Song's laboratory focuses on understanding the mechanisms of cell death, including apoptosis, ferroptosis, pH-dependent cell death, and immunogenic cell death.
The Wang lab applies single-molecule fluorescence biophysical, quantitative biochemical, structural, and genetics approaches to unravel the intricate relationships between structure, dynamics and function in complex dynamic biological systems. Our primary goal is to understand the dynamic mechanisms of cytosolic and mitochondrial protein synthesis and how they are dysregulated in human diseases.
Our lab is studying novel regulatory mechanisms that control innate immunity in intestinal health and disease.
The Ding lab is led by Dr. Kan Ding, an Associate Professor and practicing neurologist who specializes in epilepsy. The lab concentrates on neurocritical care and post-traumatic epilepsy, with the goal of advancing strategies for diagnosis, treatment, and rehabilitation to improve care for those with epilepsy.
At the Fu Lab of human neuroscience we investigate the neural bases of cognitive control.
The Nanes Lab investigates how the keratin intermediate filament cytoskeleton organizes cell regulatory circuits during skin development, wound healing, and cancer.
The Beckham lab is a dynamic multidisciplinary laboratory that studies viral pathogenesis and neuroimmune responses.
A major focus of the Patwardhan Lab is translational research into mechanisms of pain and potential treatment.
We are interested in taking bioinformatics and data integration approaches to gain insights into cancer metabolism, inborn errors of metabolism, and lung neoplasm.
