Nov 2024
Lab lunch before Thanksgiving.
Nov 2024
Vivek's paper on tubby beta barrel region in cargo trafficking published in MBoC.
View paper.
August 2024
Our collaborative paper describing deconstruction of cilia in cerebellar granule neurons published in JCB.
Permanent deconstruction of intracellular primary cilia in differentiating granule cell neurons
August 2024
Saikat presented at the International Neural Tube Defects meeting in Vancouver, BC.
Dr. Judith Hall, who first described Pallister Hall syndrome patients with GLI3 mutations that form repressor, was at the meeting. View NTD Program highlights.
July 2024
Amy Ternida, a high school STARS program summer student in the lab, presenting poster on her project working together with Vivek.
View Stars Program Highlights
May 2024
Vivek and Yu on a Mississippi river ride with Saikat in the FASEB meeting
View Meeting highlights
May 2024
FASEB cilia meeting: Saikat presents GPR161 structure paper, Vivek presents TULP-IFT-A binding story.
View Meeting highlights
Feb 2024
Our collaborative paper with Manglik lab on GPR161 regulation by sterols and auto-activation published in NSMB!
View Article
Nov 2023
Article on context dependent regulation of hedgehog signaling by cilia in cover of PLOS Genetics Nov 2023 issue!
View Article
Oct 2023
Sun-hee and Kevin's paper on context dependent regulation of hedgehog signaling by cilia was accepted in PLOS Genetics!
Oct 2023
Saikat presented in the AKAP meeting in London! He talked about the new insights into GPR161 structure, activation by sterols and function.
Sep 2023
Vivek received the travel award for attending the ASCB meeting and will present his research in a minisymposium on Protein Compartmentalization and Sorting!
Aug 2023
Anatupenda Daphrose, a STEP-UP summer research program high school student, presented her project in NIH, Baltimore.
Apr 2023
Benji Popokh, a first year medical student, was just selected to the Medical Student Summer Research Program 2023 to work in the Mukhopadhyay lab. He will work on understanding role of ciliary signaling in medulloblastoma.
Feb 2023
IFT-A structure paper from collaborator Ji Sun garners a lot of online attention.
View Article
Nov 2022
Saikat presents in the International Neural Tube Defects meeting in Austin
Sep 2022
Past grad student Nipunika receives CTF postdoc fellowship! CONGRATS!!! She had 10+ papers from her grad work in Saikat's lab.
July 2022
Saikat presents in the FASEB PKD meeting in Lisbon, Portugal
June 2022
Saikat presents in the FASEB cilia meeting in Tuscon, Arizona
May 2021
PKD Foundation Researcher Spotlight for Vivek
August 2020
Current projects in Mukhopadhyay Lab
Saikat talks about current projects while welcoming incoming class of 2020.
Saikat talks about current projects while welcoming incoming class of 2020.
May, 2020
JCB paper recommended by Michael Olson at Faculty Opinions
December 2019
Lab lunch before holidays 2019
Sept, 2019
Nipunika receives best postdoc talk award in Neural Tube Defects Meeting 2019, Boston. Congrats!
Aug, 2019
Vivek gets the 2nd best talk award in FASEB Cilia Meeting. Congrats!
July 2019
Nipunika gets travel award to attend Neural tube defects meeting 2019
July 2019
Vivek gets PKD foundation postdoctoral fellowship
June 2019
Society of Developmental Biology Award 2019
Vivek gets the Society of Developmental Biology Award 2019 for attending the Biology of Cilia and Flagella FASEB Summer Research Conference. Congrats!
May 2019
Developmental Biology Cover Article on Forebrain development
Role of Gpr161 in forebrain development.
Immunofluorescence image of mouse postnatal day 0 cingulate cortex from conditional knockout of the G-protein-coupled receptor, Gpr161 stained for cortical neuron markers Satb2 (red) and FoxP1 (green) showing excess gyrus formation (polymicrogyria). Shimada et al. demonstrate that derepression of sonic hedgehog signaling upon Gpr161 deletion causes forebrain defects such as that shown in the image, and ventricular abnormalities, including ventriculomegaly and periventricular nodular heterotopia. Image constructed by Bandarigoda N. Somatilaka and John Shelton. See article by Shimada et al., pages 47-62 in volume/issue 450/1.
May 2019
Nipunika's Graduation Commencement, May 2019
RNipiunika's graduation commencement, May 2019.
Sun-hee, Nipunika, Saikat, Vivek, and Kevin.
Congrats!
March 2019
Kidney cystogenesis paper published in Current Biology
Sun-hee and Nipunika's paper on Tulp3-mediated ciliary trafficking in renal cystogenesis published in Current Biology
April 2018
Bandarigoda Nipunika Somatilaka successfully defends her Ph.D.
“Role of Primary Cilium-Mediated Signaling in Development, Disease and Cancer”
March 2018
Switch for most common malignant pediatric brain tumor
February 2018
Cover article in Cell Reports (Jan 30, 2018)
Cover article in Cell Reports (Jan 30, 2018) on the role of Gpr161 in repressing medulloblastoma
February 2017
JCB highlights trafficking of membrane proteins
Drs. Mukhopadhyay and Badgandi, along with colleagues, are highlighted in the article titled "Tubby proteins prove their adaptability" in Journal of Cell Biology for their research on the trafficking of membrane proteins to cilia.
Tubby proteins prove their adaptabilityApril 2016
JCB highlights paper from Mukhopadhyay lab
Dr. Mukhopadhyay's recent paper on Gpr161 removal from cilia was highlighted in the Journal of Cell Biology. The paper, "Smoothened determines β-arrestin–mediated removal of the G protein–coupled receptor Gpr161 from the primary cilium," was published March 21, 2016.
Smoothened determines β-arrestin–mediated removal of the G protein–coupled receptor Gpr161 from the primary ciliumFebruary 2013