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Our research is focused on mechanisms underlying acute kidney injury and sepsis.  Our laboratory has implicated mitochondrial maintenance via PGC1alpha and NAD+ as a novel pathway for resilience against acute physiological stressors.

Our lab focuses on membrane proteins in cholesterol biogenesis, transport, and signaling using multiple approaches from protein engineering, to x-ray crystallography and cryo-EM.

The Sun Lab is focused on developing novel imaging probes for noninvasive assessment of specific biomarkers implicated in disease initiation, progression, or regression, and exploring the translational roles of imaging probes and/or methodologies in clinical medicine practice with the ultimate goal to improve the outcome of patient care.

Jan’s Lab is interested in understanding the dynamics of protein-RNA complexes during ribosome biogenesis. We are particularly focused on the roles of ATPases in coordinating ribosomal RNA processing and remodeling events, as well as the importance of these enzymes in signaling between the ribosome biogenesis pathway and the cell cycle machinery.

The Lin lab develops theoretical models and uses computational tools to find the performance limits of complex biological systems. 

Glen Liszczak  laboratory is exploring cellular signaling mechanisms that regulate transcription and preserve genome stability.

The Shahmoradian lab investigates the roles of domain-specific neuronal proteins using advanced cryo-imaging techniques to understand their impact on cellular dynamics and neurological health.

The work of Deborah Carlson, Ph.D., focuses on characterizing the inflammasome mediating the inflammatory response in the heart following thermal injury and thermal injury complicated with sepsis. 

We conduct state-of-the-art clinical trials in the field of cardiovascular diseases, offering patients access to advanced clinical therapies that would otherwise not be available.

Shay Lab is interested in the relationships between aging and cancer and have focused on the role of the telomeres and telomerase in these processes.

Our lab is interested in addressing a fundamental question of cell biology: How are organelles spatially organized?

The Moe Lab specializes in translational pathophysiology that spans from individual molecules, in vitro cell models, in vivo animal models, to metabolic human studies. 

Interrogating the genome to better understand the mechanisms causing autism spectrum disorder and other neurodevelopmental disorders and inform innovative therapies

Malloy Lab has all the tools necessary for students at all levels to lean about metabolic imaging of physiology and disease and I am excited to participate.

The overall focus of the Ram Mani Lab is to study the molecular genetic and epigenetic events associated with cancer development.

The Jamieson Lab lab is shipping AI solutions safely!

We focus on the discovery of targeted therapies for major drivers of cancer using protein chemistry, enzymology, structural biology, informatics and cell biology. Some of our favorite targets are RAS and kinase proteins.

The McAdams Lab at UT Southwestern uses neuroimaging and behavioral measures to investigate the connections between social, psychological, and biological aspects of eating disorders.

Shawna D. (Smith) Nesbitt, M.D., M.S., studies hypertension in African-Americans, insulin resistance, and hyperlipidemia. 

Malter Lab focuses on exploring and characterizing intracellular signaling pathways in the immune and nervous systems and identifying how defects/abnormalities can lead to disease.