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The major interest of my lab is to understand the transcriptional regulatory mechanisms involved in human diseases with a focus on cardiovascular diseases and cancer. 

Our goal is to provide state-of-the-art expertise for analysis of exome and genome sequencing.

The ultimate goal of the Nijhawan-De Branander Lab is to discover first in class drugs for the treatment of cancer. 

Xin Liu Lab is interested in understanding the regulation of transcription and chromatin dynamics underlying many fundamental biological processes including differentiation, development, and oncogenesis.

Petroll Lab applies engineering approaches and design principles to the investigation of fundamental clinical and biological problems in ophthalmology, while providing training to graduate students, medical students, and post-docs. 

The focus of Dr. Agarwal's research has been on mechanisms of steroid action with emphases on: 1) structure-activity relationships of ligand-steroid receptor interactions, and 2) steroid metabolism.

Our laboratory actively studies disease processes that disrupt normal metabolism.

The Zhang lab studies intra- and inter-molecular interactions to understand how signaling proteins are regulated, using biochemistry, X-ray crystallography, cryo-EM and cell biology.

Our lab is using various approaches to explore this biology and develop new treatments with a focus on targeting tumor intrinsic factors such as genetic programs like the epithelial to mesenchymal transition that coordinate with infiltrating immune cells in enhance therapeutic resistance and assist distant spread.

Our goal is to track the signaling dynamics of individual effectors and toxins in living cells, using a combination of fluorescent genetic reporters, microinjection of labeled bacterial proteins, and live cell imaging techniques. 

The Arteaga laboratory has a longstanding interest in understanding the molecular pathways that drive breast cancer progression and influence response to therapies.

The ultimate goal of the Kittler Lab's research is to develop novel therapeutic approaches that target transcription factors, which play important roles in common solid tumors (brain, breast, lung and prostate cancer) and could therefore have translational potential.

Tsai Lab studies the cellular and molecular mechanisms of synapse and neural circuit development.

Our research focuses on two main areas: hyperpolarized 13C, 15N, 89Y and 107, 109Ag compounds, and conventional lanthanide-based T1 shortening and paraCEST imaging agents.

Our laboratory has characterized many of the transporters responsible for proximal tubule acidification and solute transport

The Kraus Lab is interested in the basic mechanisms of nuclear signaling and gene regulation by small molecules and how these signaling pathways relate to human physiology and disease states.

Our research is largely aimed at understanding how an organism detects mechanical force.

Mukhopadhyay Lab research aims to understand how the primary cilium regulates downstream pathways to ultimately drive morphogenesis in different tissues. We undertake a multi-pronged approach including proteomics, cell biology, biochemistry, reverse genetics, and generation of innovative mouse models to study regulation of signaling pathways by cilia in in cellular and organismal contexts.

Our lab focuses on the molecular and cellular mechanisms underlying cell fate specification during blood vessel development and organogenesis.

Roberts Lab focuses on understanding the cellular and circuit mechanisms for behavioral learning, learning from social experiences and from example.