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We use in vivo models of ischemic acute kidney injury in mice, and in vitro model systems to perform detailed studies of proinflammatory genes activated by renal ischemia/reperfusion.

The central goal of the Dauer Lab is to unravel the molecular and cellular mechanisms of diseases that disrupt the motor system. In exploring these diseases, we also aim to understand a fundamental question relevant to CNS disease generally: what factors determine the selective vulnerability of particular cell types or circuits to insults? Our primary focus is on Parkinson’s disease and inherited forms of dystonia. We focus our efforts on disease genes that cause these disorders, employing a range of molecular, cellular, and whole animal studies to dissect the normal role of disease proteins, and how pathogenic mutations lead to disease.

Explore the Vongpatanasin Lab at UT Southwestern, specializing in research on neural control of blood pressure, autonomic dysfunction, and the impact of nutrition and hormones on cardiovascular health. Discover clinical studies, lab members, and featured publications advancing hypertension and autonomic research.

Elizabeth Chen Lab focuses research on cell-cell fusion, drosophila myoblast fusion, invasive membrane protrusions, actin binding and bundling proteins, and mechanoresponsive proteins.

The Saxena lab's research interests include Icodextin in high peritoneal transporters; Kremezin study in patients with chronic kidney disease; SV40 in focal segmental glomerulosclerosis; molecular studies in lupus nephritis.

Chen Lab is broadly interested in mechanisms of signal transduction, namely how a cell communicates with its surroundings and within itself.

The Whitehurst Lab uses RNAi-based functional genomics to identify gene products that support viability and/or modulate chemotherapeutic sensitivity in tumor cells. 

My research interests include prevention of progression of renal diseases, diagnoses, and management of lipid disorders in renal disease, hypertensive nephrosclerosis, the role of angiotensin II converting enzyme inhibitors, and angiotensin II receptor blockers in renal disease. 

The Reinecker laboratory unravels and targets molecular mechanisms of key human genetic variants that cause chronic inflammatory diseases and cancer by creating novel genetic mouse and human organotypic model systems.

The Bioinformatics Lab provides services to manage and analyze next-generation sequencing data.

Zheng Lab is dedicated to women’s health care, specializing in gynecologic pathology, particularly in oncologic and hormone related pathology within the GYN Pathology field.

Discover the Miguel Vazquez Lab at UT Southwestern, leading research in chronic kidney disease, diabetes, and hypertension. Learn about the IDC-Pieces study—a large, NIH-supported clinical trial improving chronic disease management through innovative care models and technology.

The James Kim Lab examines the communication between epithelia and stroma through the lens of fundamental developmental pathways such as Hedgehog, Wnt, and Notch pathways.

We study bacterial colonization of the intestinal tract, to understand how both benign and pathological bacteria affect their environment. Our long-term goal is to treat intestinal diseases by genetically engineering bacteria in vivo.

The Marciano laboratory investigates fundamental aspects of kidney development and regeneration, in both health and disease.

Dr. Garg's research focuses on diabetes, insulin resistance, and disorders of adipose tissue.

The Rohatgi Lab focuses on the role of reverse cholesterol transport in atheroprotection.

We are interested in the relationship between metabolism and cell type. We focus on the metabolism of hematopoietic stem cells (HSCs) and their progeny including cells of the myeloid and T cell lineages.

Our goal is to employ cryo-EM to determine high resolution structures of important membrane protein complexes involved in cellular signaling, including cellular receptors and ion channels. We also combine structural approaches with functional studies to reveal the structure-function relationships of these membrane proteins.

We study the role of chromatin regulation in cell fate decisions.