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Kim (Jaehyup) lab studies the mechanism of immune regulatory receptor regulation with a special focus on ligand identification and modulation.

The vision of the lab is to further understand the pathogenesis of autoimmunity of the central nervous system through basic science and translational research.

We use live-cell microscopy, nano-rheology, and synthetic biology to understand oocyte ageing, embryogenesis, and cancer onset.

Qiao lab focuses on mechanisms of cancer immunotherapy and immune-related adverse events (irAEs)

Our lab focuses on investigating the brain circuits implicated in treatment resistant depression with the ultimate goal of developing novel therapies for this devastating disease.

The Sun Lab studies the most numerous cells in the brain, called “glial cells”.

The goal of the Center is to support pre-clinical research that uncovers the mechanisms of pediatric musculoskeletal disorders and explores potential new therapies.

The Greenberg Lab focuses on translational research relative to autoimmune disorders of the central nervous system.

We are interested in the circuit mechanisms of how the cerebellum helps the brain to work better in health and disease.

The discovery of ANP many years ago sparked interest in the use of natriuretic peptides to diagnose and treat heart failure and other salt-retaining disorders. Since then, there have been successes and failures. A more comprehensive understanding of the natriuretic peptide system, including the role of noncardiac factors such as race/ethnicity, may encourage more targeted approaches. One of the original insights of de Bold et al, was that the heart is an endocrine organ. Endocrine therapies are administered to individuals with specific evidence of endocrine dysfunction, not to capture short-term beneficial effects. For instance, thyroid hormone is given only to patients in whom hypothyroidism is demonstrated, not based on its metabolic actions. Studies are warranted to determine whether a similar strategy for the heart’s endocrine system can advance the prevention and treatment of cardiometabolic disease. CMRU is strategically positioned to advance research toward this important strategic goal. 

The Tower lab integrates multi-omics-based approaches in the fields of musculoskeletal development, homeostasis, repair and regeneration. 

We investigate how the immune system and gut microbiota influence brain function and behavior. We use molecular, behavioral, anatomical, and immunological approaches in the lab. In parallel, we collaborate with clinical groups to examine the role of inflammatory and gut-brain mediators in psychiatric illness.

The Foster Lab research program represents a “best in class” translational research approach in an enriched, multidisciplinary environment. Foster's academic activities include a strong translational research program, a comprehensive teaching portfolio, science outreach, contribution to local, national, and international peer review and knowledge translation.

Our mission is to better unravel the causes and mechanisms underlying tremor disorders as well as understand the clinical features of these disorders.

Under the guidance of director Dr. Daolin Tang, the research group focuses on basic, translational and clinical application research on damage-associated molecular patterns (DAMPs) signaling pathways. Inflammation is a fundamental response to infection and injury in all multicellular organisms. The danger hypothesis states that endogenous molecules (protein and non-protein) released during cell death or tissue damage can trigger inflammation in the absence of infection, collectively referred to as DAMPs. We are particularly interested in elucidating the molecular mechanisms underlying stress-induced cellular defense and cell death signaling in normal and cancer cells, and how release of DAMPs modulates immune responses in disease.

Kong lab aims to harness the cutting-edge technologies in human genetics and genomics, immunology, and molecular biology to better understand the pathogenesis of gastrointestinal inflammation.

Dr. Prinz's research is focused on the tiny organelles within cells that do the cell’s work, much like the organs in a human body. He is best known for studies into the exchange of fats (also called lipids) between organelles at so-called membrane contact sites where organelles come in close contact within a cell. 

The Monson Lab is dedicated to understanding how B cells and T cells impact pathology of disease in the central nervous system.

The Saha Lab.

We are working at the interface of nanotechnology, drug delivery, and tumor immunology

The Tong lab studies the cellular and molecular mechanisms of cardiovascular diseases associated with systemic metabolic disorders, particularly heart failure with preserved ejection fraction (HFpEF) and atrial fibrillation (AF), with an eye toward translating these findings into innovative solutions to clinical problems.