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spinal cord injury, wound, pressure ulcer

We believe that understanding the basic biology of the schistosomes is key to developing the next generation of anti-schistosome drugs and vaccines. We also contend that by studying the basic biology of these fascinating organisms, we can better understand important basic biological processes common to all animals, including humans. For that reason, we study schistosomes from multiple angles using a variety of modern molecular approaches.of the lab. 

We are investigating how protein homeostasis (the maturation and turnover of enzymes) interacts with lipid homeostasis.

Our research endeavors are dedicated to pioneering the development of virtual reality simulators tailored for surgical training, harnessing the power of cutting-edge technologies such as artificial intelligence, automated systems, and advanced deep learning algorithms. Central to our work is the creation of AI-driven solutions for automated surgical video segmentation, precise identification of anatomical structures, surgical tool recognition, and comprehensive skills assessment.

Our lab currently studies hypoxia, prolyl hydroxylase, and VHL signaling in cancer, especially breast and renal cell carcinomas.

Ascending somatosensory circuitry that shapes the perception of touch and pain. We study the development, function and dysfunction of ascending somatosensory pathways.

The Camacho Lab focuses on understanding key genetic events that lead to cancer in an effort to identify novel targets that will help improve existing therapies

The Wu Laboratory mainly focuses on using human primary nasal and oral epithelium culture to gain novel insights in virus-host interactions.

The Liu Lab is Interested in developing and evaluating novel therapies, notably targeting tumor vasculatures.

Translational biophotonics for noninvasive detection of systemic disease.

The Sharma Lab is interested in investigating intermediary metabolism utilizing carbon-13 stable isotope tracers in conjunction with magnetic resonance spectroscopy (MRS), magnetic resonance imaging (MRI), and mass spectrometry (MS).

We are interested in how epithelial tissues sense and respond to injury.

We mine large-scale data for biological discoveries.

Research conducted by the Nomellini Lab utilizes animal models as well as human samples to examine the interaction between the innate and adaptive immune responses that occur after injury or infection, and the heterogeneity of the immune responses that occur in each individual. Led by Vanessa Nomellini, M.D., Ph.D., our lab ultimately aims to develop personalized immune therapies to reverse the immunosuppression that can occur in ICU survivors.

Zaman’s Lab focuses on the design and development of novel cutting-edge multi-mode imaging systems to overcome current limitations in clinical systems. Most recent research project is involved with the design and developed of a multimode catheter-based imaging system called a Circumferential Intravascular Radioluminescence Photoacoustic Imaging (CIRPI) for early detection of thin-cap-fibro-atheroma (TCFA), the underlying causes of coronary artery disease, one of the leading causes of morbidity and mortality in the USA and worldwide. Further, the CIRPI system characterizes the plaques based on disease tissue compositions to unravel their complex structures. This CIRPI system integrates optical, photoacoustic, radioluminescence and ultrasound imaging. We seek to better understand the underlying causes of the disease mechanisms. We are dissecting the role of TCFA perturbations on vascular wall processes during atherosclerosis progression. Our lab also studying novel molecular imaging methods to study coronary arterial disease, carotid stenosis, and myocardial ischemia in subcellular level.

Kim (Jaehyup) lab studies the mechanism of immune regulatory receptor regulation with a special focus on ligand identification and modulation.

The vision of the lab is to further understand the pathogenesis of autoimmunity of the central nervous system through basic science and translational research.

We use live-cell microscopy, nano-rheology, and synthetic biology to understand oocyte ageing, embryogenesis, and cancer onset.

Qiao lab focuses on mechanisms of cancer immunotherapy and immune-related adverse events (irAEs)

Our lab focuses on investigating the brain circuits implicated in treatment resistant depression with the ultimate goal of developing novel therapies for this devastating disease.