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Understanding brain circuits in disease and cognition to develop restorative neuromodulation. 

Dr. Brunoni's research focuses on developing innovative therapeutic strategies using transcranial direct current stimulation, transcranial magnetic stimulation, and other neuromodulation techniques for treating major depressive disorder, bipolar disorder, OCD, schizophrenia, and post-COVID cognitive symptoms.

The Cardiovascular Pharmacotherapy Research Lab integrates molecular epidemiology, clinical pharmacology, clinical trials and population health science to identify new pathways and therapeutic strategies for the prevention of heart failure. Our team conducts cross-disciplinary, mechanism-focused clinical research to translate biologic discoveries into interventions with meaningful public health impact.

Research lab at UT Southwestern for Mohan Krishnan, Ph.D.

Our laboratory is interested in studying the intersection between lung cancer and immunology. We are currently focused on co-opting innate immune signaling pathways and tumor-associated T cell populations to target diverse subsets of lung cancer.

The Sankary Neuroethics Lab at UT Southwestern explores the ethical dimensions of neuroscience and neurosurgical innovation.

Neuron-cancer interactions that promote tumor growth and disrupt neural circuits. 

The central goal of Dr. Asch's research is to uncover the mechanistic underpinnings of how stress and trauma affect brain function, with a particular emphasis on how these experiences shape mental health outcomes with the aim to contribute to the development of novel interventions designed to mitigate the harmful effects of stress and trauma, foster resilience, and ultimately improve overall 
health and well-being.

The Bartelt Lab is focused on understanding the epigenetic basis of cerebellar neurodegenerative disorders to develop holistic gene therapies. Using single-cell and spatial sequencing approaches, we profile healthy and diseased states to identify gene regulatory mechanisms in disease and utilize functional genomic tools to advance therapeutic approaches. 

Medical Artificial Intelligence and Automation

The Sweat lab studies how perturbations in cardiac gene expression result in arrhythmias, with a focus on atrial fibrillation. We apply single-cell multiomics and epigenetics approaches to gain insight into mechanisms of arrhythmia and potential new treatment approaches231`

The Voice Behavior and Rehabilitation Laboratory, led by Dr. Laura Toles, performs research in the field of Otolaryngology with focus on individual differences, personality and voice, phonotrauma, vocal behavior, and improving therapeutic outcomes.

Shi Lab focuses on developing AI systems for healthcare, with an emphasis on large language models, agentic AI, clinical informatics, personalized medicine, tool/retrieval-augmented learning, reasoning, and data-centric AI. 

The Kelesidis Lab studies the cross between viral infections and mechanisms of associated end organ damage with a goal to develop novel therapeutic treatments. 

Our goal is to understand and exploit the immunogenic properties of tumor irradiation in integrating it with immunotherapy to improve cancer patient outcome.

Our mission is to innovate, develop, and apply biomedical technology to empower cancer research.

Our mission is to improve the care of breast cancer patients through cutting-edge translational research at the interface of clinical oncology, cancer biology, molecular genetics, and translational genomics.

The Moreland and Potera Labs utilize basic science approaches, in vivo models, and clinical studies to investigate cellular functions of the innate immune system.

The Davis Lab is part of the Section of Molecular Medicine in the Department of Radiation Oncology

The Brekken laboratory, located in the Hamon Center for Therapeutic Oncology Research, studies tumor-host interactions with a particular emphasis on extracellular matrix (ECM) and angiogenesis.