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The Sibley lab focuses on developing and validating emerging imaging technologies to understand the lymphatic system and guide clinical management for patients with lymphatic diseases such as lymphedema.

We are a group of physicists, biophysicists, cell biologists, and “computationalists” interested in the spatiotemporal organization of cell surface receptors, the mechanisms underlying it, and its consequences for cell signaling. We utilize light microscopy, particularly single-molecule and super-resolution imaging, to monitor molecular behavior in its native cellular environment, and we develop computer vision and machine learning approaches to quantitate the observed behavior and gain insight beyond what the eye can see.

The Zechner Lab applies molecular and cell biology techniques to investigate how mammalian cells regulate their phosphate homeostasis and sensing using the ubiquitous phosphate transporter PiT1/SLC20A1 as a model.

Research lab at UT Southwestern for Mohan Krishnan, Ph.D.

Our lab studies how cells organize metabolic pathways to meet changing metabolic demands. We explore how higher-order enzyme assemblies and organelle dynamics create compartmentalized metabolic environments. By uncovering the spatiotemporal regulation of metabolism, we aim to reveal fundamental principles of metabolic control relevant to health and disease.

Understanding brain circuits in disease and cognition to develop restorative neuromodulation. 

Dr. Brunoni's research focuses on developing innovative therapeutic strategies using transcranial direct current stimulation, transcranial magnetic stimulation, and other neuromodulation techniques for treating major depressive disorder, bipolar disorder, OCD, schizophrenia, and post-COVID cognitive symptoms.

Medical Artificial Intelligence and Automation

Our goal is to understand and exploit the immunogenic properties of tumor irradiation in integrating it with immunotherapy to improve cancer patient outcome.

Our mission is to innovate, develop, and apply biomedical technology to empower cancer research.

Our mission is to improve the care of breast cancer patients through cutting-edge translational research at the interface of clinical oncology, cancer biology, molecular genetics, and translational genomics.

The Moreland and Potera Labs utilize basic science approaches, in vivo models, and clinical studies to investigate cellular functions of the innate immune system.

The Davis Lab is part of the Section of Molecular Medicine in the Department of Radiation Oncology

The Brekken laboratory, located in the Hamon Center for Therapeutic Oncology Research, studies tumor-host interactions with a particular emphasis on extracellular matrix (ECM) and angiogenesis.

Our focus is on gaining a greater understanding of how bacteria on the skin surface affect skin health and diseases.

The Schoggins Lab studies innate immunity at the virus-host interface. We are interested in mechanisms of cellular antiviral defense and the role these responses play during viral disease.

Chen lab studies how dysregulation of RNA synthesis and degradation drives childhood cancers with the ultimate goal of identifying new therapeutic vulnerabilities to exploit in treating them.

The Orth lab is interested in elucidation the activity of virulence factors from pathogenic bacteria so that we can gain novel molecular insight into eukaryotic signaling systems.

The Ready Lab is engaged in the discovery and synthesis of biologically active small molecules

For decades, the field of tuberculosis (TB) immunology has focused on T cell mediated protection, yet Mycobacterium tuberculosis (Mtb) still impacts one in four individuals worldwide today.