University of Texas Southwestern Labs: Where Breakthroughs Happen

Latest Research News

Study links female sex hormones to progression of eye disease

Jul 08, 2025

Female sex hormones can significantly enhance the progression of the rare neurodegenerative eye disease retinitis pigmentosa (RP), according to a preclinical study by researchers at UT Southwestern Medical Center. The findings, published in Science Advances, may lead to therapeutics to slow progression of the disease and help clinicians assess the risk of hormone therapies for female patients with genetic markers for the disease.

Female sex hormones can significantly enhance the progression of the rare neurodegenerative eye disease retinitis pigmentosa (RP), according to a preclinical study by researchers at UT Southwestern Medical Center. The findings, published in Science Advances, may lead to therapeutics to slow progression of the disease and help clinicians assess the risk of hormone therapies for female patients with genetic markers for the disease.

Latest Research News

Ridding cells of mitochondria sheds light on their function

Jul 03, 2025

By using a genetic technique they developed that forces cells to rid themselves of mitochondria, UT Southwestern Medical Center researchers are gaining new insights into the function of these critical organelles.

By using a genetic technique they developed that forces cells to rid themselves of mitochondria, UT Southwestern Medical Center researchers are gaining new insights into the function of these critical organelles.

Latest Research News

Hormone may hold key to longer life, improved metabolic health

Jul 01, 2025

Fat cells genetically altered to overproduce a hormone called FGF21 resulted in improved metabolic health and an extended lifespan in mice that were fed a high-fat diet, UT Southwestern Medical Center researchers report. The findings, published in Cell Metabolism, could lead to new interventions that have the same positive effects in humans.

Fat cells genetically altered to overproduce a hormone called FGF21 resulted in improved metabolic health and an extended lifespan in mice that were fed a high-fat diet, UT Southwestern Medical Center researchers report. The findings, published in Cell Metabolism, could lead to new interventions that have the same positive effects in humans.

Latest Research News

High phosphate diet impacts nervous system, induces hypertension

Jun 30, 2025

Diets rich in phosphate additives, commonly found in processed foods, can increase blood pressure by triggering a brain signaling pathway and overactivating the sympathetic nervous system that regulates cardiovascular function, UT Southwestern researchers discovered.

Diets rich in phosphate additives, commonly found in processed foods, can increase blood pressure by triggering a brain signaling pathway and overactivating the sympathetic nervous system that regulates cardiovascular function, UT Southwestern researchers discovered.

Latest Research News

New tool sheds light on where RNA is found in cells

Jun 26, 2025

A new tool called PHOTON, developed by scientists at UT Southwestern Medical Center, can identify RNA molecules at their native locations within cells – providing valuable clues to where different RNA species are distributed spatially in response to various cellular cues.

A new tool called PHOTON, developed by scientists at UT Southwestern Medical Center, can identify RNA molecules at their native locations within cells – providing valuable clues to where different RNA species are distributed spatially in response to various cellular cues.

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Facts and Figures

Six Nobel Prize recipients since 1985

Alumni Nobel Laureates include Joseph Goldstein and Linda Buck.

14 Howard Hughes Medical Institute Investigators
Best Hospital in DFW UT Southwestern's William P. Clements Jr. University Hospital has been ranked No. 1 in Dallas-Fort Worth for eight straight years.
$716 million per year to fund faculty research

Faculty Awards & Honors

25 National Academy of Sciences
24 National Academy of Medicine
14 American Academy of Arts and Sciences