In diseases like cancer, signaling pathways can be corrupted by mutations that cause the cells to grow and spread uncontrollably. Our lab is interested in understanding how these defective pathways reprogram cellular metabolism to drive cancer growth.
Jer-Tsong Hsieh Lab research interests focus on key molecular mechanisms leading to urologic cancer progression, development of precision medicine of cancer therapy assisted with non-invasive molecular imaging.
Ming-Chang Hu Lab strives to offer novel insight into the cellular and molecular mechanisms of AKI progression to CKD and cardiovascular diseases (vascular calcification and uremic cardiomyopathy) development in CKD, and set up a solid basis for preclinical and clinical study in the future.
Publications for Dr. Emina Huang's Lab
The research of the Huang Laboratory focuses on understanding the function of fibroblast progenitor cells and fibroblasts in regulating the immune system.
Our laboratory is interested in the molecular mechanisms governing cytokine receptor signal transduction in hematopoietic stem and progenitor cells, and understanding how deregulation in these mechanisms results in hematological malignancies and cancer.
The Huber lab is focused on understanding how activity-regulated transcription and translation in neurons controls synapse and circuit plasticity and development.
Huen Lab studies how metabolic adaption promotes survival during sepsis and how the kidneys contribute to systemic metabolism during inflammation.
Our goal is to provide state-of-the-art expertise for analysis of exome and genome sequencing.
Our lab focuses on the use of cardiac magnetic resonance imaging (CMR) in pediatric and congenital heart disease.
Our laboratory actively studies disease processes that disrupt normal metabolism.
The Institute for Exercise and Environmental Medicine is a 40,000 square-foot research facility with 12 UTSW faculty working in multiple departments and divisions (Internal Medicine/Cardiology/Pulmonary, Neurology, PM&R, Anesthesiology, Applied Physiology) with up to 20 postdocs, and 40 staff on 70 active protocols and 15 federal grants. It is a research enterprise devoted to the study of human physiology and the limits to human functional capacity in health and disease.
Interventional psychiatry is treatment that combines brain stimulation with medication for difficult-to-treat mental health disorders. At UT Southwestern Medical Center, our psychiatrists have advanced training and expertise in caring for people with treatment-resistant mental health disorders.
We specialize in the latest advances in brain stimulation to bring relief to people who haven’t had success with traditional treatments.
The Ishii Laboratory is interested in understanding the bidirectional relationship between brain function and systemic metabolism with an emphasis on metabolic deficits in Alzheimer’s disease and how it differs from normal aging. Our laboratory focuses on generating hypotheses derived from open questions in clinical neurology and neuroendocrinology, testing these hypotheses using molecular genetics and neuroscience techniques in the laboratory, and whenever possible verifying these findings in clinically relevant human research studies.
