The Advanced Integrative Molecular Probe Collaboration's mission is to develop new imaging agents in a multidisciplinary approach to monitor, understand and cure disease at an early stage.
Our research endeavors are dedicated to pioneering the development of virtual reality simulators tailored for surgical training, harnessing the power of cutting-edge technologies such as artificial intelligence, automated systems, and advanced deep learning algorithms. Central to our work is the creation of AI-driven solutions for automated surgical video segmentation, precise identification of anatomical structures, surgical tool recognition, and comprehensive skills assessment.
Our mission is to improve the care of breast cancer patients through cutting-edge translational research at the interface of clinical oncology, cancer biology, molecular genetics, and translational genomics.
Our goal is to track the signaling dynamics of individual effectors and toxins in living cells, using a combination of fluorescent genetic reporters, microinjection of labeled bacterial proteins, and live cell imaging techniques.
Our group initially investigated a novel immune checkpoint inhibitor targeting a rare heparan sulfate (rHS) in melanoma treatment. Collaboratively, we explored the potential of a single-domain humanized rHS antibody (1A7 clone) that inhibits DC-HIL function and also angiogenesis and chemokine effects linked to diverse cancer progression signaling pathways. This experience provided insights into rHS-targeting as a promising approach to melanoma therapy.
The Arteaga laboratory has a longstanding interest in understanding the molecular pathways that drive breast cancer progression and influence response to therapies.
The central goal of Dr. Asch's research is to uncover the mechanistic underpinnings of how stress and trauma affect brain function, with a particular emphasis on how these experiences shape mental health outcomes with the aim to contribute to the development of novel interventions designed to mitigate the harmful effects of stress and trauma, foster resilience, and ultimately improve overall health and well-being.