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Publications for Dr. Emina Huang's Lab

The research of the Huang Laboratory focuses on understanding the function of fibroblast progenitor cells and fibroblasts in regulating the immune system.

Our laboratory is interested in the molecular mechanisms governing cytokine receptor signal transduction in hematopoietic stem and progenitor cells, and understanding how deregulation in these mechanisms results in hematological malignancies and cancer.

The Huber lab is focused on understanding how activity-regulated transcription and translation in neurons controls synapse and circuit plasticity and development.

Huen Lab studies how metabolic adaption promotes survival during sepsis and how the kidneys contribute to systemic metabolism during inflammation.

Our goal is to provide state-of-the-art expertise for analysis of exome and genome sequencing.

Our laboratory actively studies disease processes that disrupt normal metabolism.

The Institute for Exercise and Environmental Medicine is a 40,000 square-foot research facility with 12 UTSW faculty working in multiple departments and divisions (Internal Medicine/Cardiology/Pulmonary, Neurology, PM&R, Anesthesiology, Applied Physiology) with up to 20 postdocs, and 40 staff on 70 active protocols and 15 federal grants. It is a research enterprise devoted to the study of human physiology and the limits to human functional capacity in health and disease. 

In the Izumi Lab, with the ultimate goal of identifying druggable molecules/pathways in pediatric genetic disorders, we investigate the molecular mechanisms of pediatric genetic disorders due to chromosomal abnormalities and chromatin protein mutations. We employ novel genetic approaches by using patient-derived samples, induced pluripotent stem cell models and mutant mouse models.

We focus on

•  Therapeutic clinical trials in infectious diseases
•  Improving outcomes through the improvement of the delivery of health services
•  Analysis of outcomes among those with infections

The Jain Lab is broadly interested in sex disparities in research on women's health, as well as the impact of sex hormones on airway diseases and immune response.

The James Kim Lab examines the communication between epithelia and stroma through the lens of fundamental developmental pathways such as Hedgehog, Wnt, and Notch pathways.

Malter Lab focuses on exploring and characterizing intracellular signaling pathways in the immune and nervous systems and identifying how defects/abnormalities can lead to disease.

The Jamieson Lab lab emphasizes AI/ML, software development, and image analysis.

We are a group of biophysicists, cell biologists and computational folks interested in the spatiotemporal organization of cell surface receptors, the mechanisms underlying it, and its consequences for cell signaling. 

The Jewell Lab investigates how organisms sense environmental nutrient fluctuations and respond appropriately, fine tuning anabolic and catabolic processes to control cell growth, metabolism, and autophagy.

Huaqi Jiang Lab studies the regulation of adult tissue homeostasis and regeneration using a genetic model system, the adult Drosophila midgut. 

The Jiang lab studies fundamental mechanisms governing how diverse cell types are generated from naive progenitor cells and how cells of different types are put together to form appropriate body structures such as limbs during embryonic development. The lab also studies how damaged cells are replenished by stem cells during tissue repair and organ regeneration in adult life. We are particularly interested in understanding how cells communicate with one another to influence their growth and fate determination and how miscommunication among different cells leads to developmental abnormality and cancer progression.

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Our lab seeks to uncover the structure-function relationship of macromolecules involved in protein misfolding — a key element of Alzheimer’s and other neurodegenerative diseases.

The research in the Johnson lab is focused on vertebrate nervous system development during the transition from proliferating neural stem cells to differentiating neurons and glia. 

We have two major areas of research: respiratory viruses and newly emerging pathogens. 

The primary research focus of the Karner lab is to create and utilize novel mouse genetic models to study the role of cellular metabolism during skeletal development and disease. 

Research in the Kim lab is focused on developing computer algorithms and statistical methods that enable accurate and rapid analysis of biological data, in particular sequencing data.

Kim (Jaehyup) lab studies the mechanism of immune regulatory receptor regulation with a special focus on ligand identification and modulation.