Dr. LoBue's BRAIN lab, short for Brain Aging, Injury, and Modulation Lab, has two lines of research in the area of aging and neurodegenerative diseases. The lab investigates the later-in-life effects of traumatic brain injury, which involves understanding the potential risk associated with developing dementia and the underlying biological pathways. The lab also studies the effects of noninvasive brain stimulation in Alzheimer’s disease and related disorders with the goal of informing the development of new treatments.
The Louros Lab uses a hybrid approach combining molecular biophysics, structural biology, and bioinformatics to investigate protein stability, misfolding, and aggregation, with a particular interest in neurodegenerative diseases.
We use in vivo models of ischemic acute kidney injury in mice, and in vitro model systems to perform detailed studies of proinflammatory genes activated by renal ischemia/reperfusion.
For decades, the field of tuberculosis (TB) immunology has focused on T cell mediated protection, yet Mycobacterium tuberculosis (Mtb) still impacts one in four individuals worldwide today.
