We research the involvement of post-translational modifications (such as ubiquitination, glycosylation) in glycogen biology and its role in glycogen metabolism related neurological and neuromuscular diseases. We also aim to develop appropriate therapies against these diseases using cutting-edge technologies such as gene therapy.
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Dr. Mizuno's laboratory studies autonomic control of the cardiovascular system, particularly the underlying alterations in circulatory control in type 1 or type 2 diabetes and Alzheimer’s disease.
The Moe Lab specializes in translational pathophysiology that spans from individual molecules, in vitro cell models, in vivo animal models, to metabolic human studies.
The Mondal Lab employs computational genomics to characterize early molecular markers of retinal neurodegenerative diseases. We investigate gene networks' underlying retinal response to dietary risk factors linked to age-related disorders. We aim to understand retinal disease mechanisms and identify therapeutic targets and lifestyle interventions that support healthy vision.
The Monson Lab is dedicated to understanding how B cells and T cells impact pathology of disease in the central nervous system.
We develop the theory and application of deep learning to improve diagnoses, prognoses and therapy decision making.
Mootha Lab uses human genetics and genomics to understand the molecular basis of Fuchs' endothelial corneal dystrophy and develop novel therapeutic strategies.
The Moreland and Potera Labs utilize basic science approaches, in vivo models, and clinical studies to investigate cellular functions of the innate immune system.
Our goal is to better understand the mechanisms that maintain adult tissues and how cancer cells hijack these mechanisms to enable the formation of tumors.
The Mosley Lab develops and applies innovative genomic and informatics approaches to identify opportunities to use genetic background to inform clinical and public health decision-making, to identify risk factors and biomarkers of disease, and to identify and reduce heath inequities in vulnerable populations.
Mukhopadhyay Lab research aims to understand how the primary cilium regulates downstream pathways to ultimately drive morphogenesis in different tissues. We undertake a multi-pronged approach including proteomics, cell biology, biochemistry, reverse genetics, and generation of innovative mouse models to study regulation of signaling pathways by cilia in in cellular and organismal contexts.
The Munshi Lab is a dedicated group of scientists seeking to identify the molecular drivers of normal cardiac rhythm and disease-associated dysrhythmias.
Muto lab leverages both cutting-edge wet-lab and multi-omics approaches to understand gene regulatory mechanism driving kidney diseases. Current projects are focused on acute kidney injury and polycystic kidney disease.
