Search Labs

The Moe Lab specializes in translational pathophysiology that spans from individual molecules, in vitro cell models, in vivo animal models, to metabolic human studies. 

The Molecular Imaging and Precision Medicine Lab has four Technology Research and Development (TR&D) projects that provide a platform on which new technology is developed and disseminated. The TR&Ds are complementary and integrated and extend from the development of reagents to detect and promote an immune reactive tumor microenvironment to the synthesis of nanodrones to treat cancer and combined small-molecule diagnostic and therapeutics (theranostic agents). We focus on generation of next-generation precision platforms, tools and techniques for tackling problems at the forefront of biomedical research with a focus on those that will lead to near-term translation.

The Mondal Lab employs computational genomics to characterize early molecular markers of retinal neurodegenerative diseases. We investigate gene networks' underlying retinal response to dietary risk factors linked to age-related disorders. We aim to understand retinal disease mechanisms and identify therapeutic targets and lifestyle interventions that support healthy vision.

The Monson Lab is dedicated to understanding how B cells and T cells impact pathology of disease in the central nervous system.

We develop the theory and application of deep learning to improve diagnoses, prognoses and therapy decision making.

Mootha Lab uses human genetics and genomics to understand the molecular basis of Fuchs' endothelial corneal dystrophy and develop novel therapeutic strategies.

The Moreland and Potera Labs utilize basic science approaches, in vivo models, and clinical studies to investigate cellular functions of the innate immune system.

Our goal is to better understand the mechanisms that maintain adult tissues and how cancer cells hijack these mechanisms to enable the formation of tumors.

The Mosley Lab develops and applies innovative genomic and informatics approaches to identify opportunities to use genetic background to inform clinical and public health decision-making, to identify risk factors and biomarkers of disease, and to identify and reduce heath inequities in vulnerable populations. 

Mukhopadhyay Lab research aims to understand how the primary cilium regulates downstream pathways to ultimately drive morphogenesis in different tissues. We undertake a multi-pronged approach including proteomics, cell biology, biochemistry, reverse genetics, and generation of innovative mouse models to study regulation of signaling pathways by cilia in in cellular and organismal contexts.

The Munshi Lab is a dedicated group of scientists seeking to identify the molecular drivers of normal cardiac rhythm and disease-associated dysrhythmias.

Muto lab leverages both cutting-edge wet-lab and multi-omics approaches to understand gene regulatory mechanism driving kidney diseases. Current projects are focused on acute kidney injury and polycystic kidney disease.

The Nair-Gill Lab dissects the cellular infrastructure that dictates immune cell survival and fate decisions.

The mission of the Najafov Lab is to understand the role of cell death in physiology and disease. Our research is focused on necroptosis and how it can be targeted to develop novel strategies for treating cancer.

The Nam lab asks how the shape of an RNA regulates its function. We study the biochemical and structural mechanisms in RNA-mediated gene regulation pathways important for normal and disease states.

The Nanes Lab investigates how the keratin intermediate filament cytoskeleton organizes cell regulatory circuits during skin development, wound healing, and cancer.

The mission of Napierala Lab is to contribute to the development of therapies and a cure for Friedreich’s ataxia (FRDA) by elucidating molecular mechanisms causing the disease, developing novel cellular and animal models of FRDA, identifying disease biomarkers and testing novel therapeutic approaches.

Shawna D. (Smith) Nesbitt, M.D., M.S., studies hypertension in African-Americans, insulin resistance, and hyperlipidemia. 

The focus of the Neuromuscular Center is the diagnosis and treatment of muscle diseases known as metabolic myopathies, including inherited disorders of muscle fat, carbohydrate, and mitochondrial muscle metabolism.

We study bacterial colonization of the intestinal tract, to understand how both benign and pathological bacteria affect their environment. Our long-term goal is to treat intestinal diseases by genetically engineering bacteria in vivo.

The Nicastro Lab studies 3D ultra-structures and cell biological functions of macro-molecular complexes inside cells.

The Ank Nijhawan research team is focused on improving outcomes for people living with or at risk for HIV, and ensuring their access to comprehensive healthcare and social support services. We also focus on individuals involved in the criminal legal system, and specifically the overlap of infectious diseases such as HIV, hepatitis, sexually transmitted infections and substance use.

The ultimate goal of the Nijhawan-De Branander Lab is to discover first in class drugs for the treatment of cancer. 

Our lab works with murine disease models and employs Biochemistry, Molecular and Cell Biology to investigate brain glycogen metabolism and related neurodegenerative diseases.