Search Labs

Please contact our team if planning neoadjuvant Adriamycin (doxorubicin), for enrollment in the HP Cardiotox Study.

The CPI lab is directed by Dr. Qing Zou and it works closely with a cross-disciplinary team (clinicians, scientists, fellows) to develop and translate novel MRI techniques for cardiopulmonary MRI for patients with congenital and acquired heart diseases. The research involves different aspects of MRI, including image acquisition and reconstruction, post-processing, quantitative image analysis, pre-clinical investigation, and clinical translation and evaluation. The lab has access to a cardiac-dedicated clinical 1.5T scanner (Philips), a research-dedicated low-field 0.55T MR scanner (Siemens), three research-dedicated 3T scanners (Philips, Siemens, GE). The lab also has access to a high-field 7T research scanner (Philips) for research on the high-field scanner. Some of the scanners also have the capability to do multi-nuclear imaging.

We conduct state-of-the-art clinical trials in the field of cardiovascular diseases, offering patients access to advanced clinical therapies that would otherwise not be available.

The work of Deborah Carlson, Ph.D., focuses on characterizing the inflammasome mediating the inflammatory response in the heart following thermal injury and thermal injury complicated with sepsis. 

Kidney disease has reached epidemic proportions in the U.S. The Carroll Lab performs basic and translational research focused on kidney development, maintenance and regeneration. 

Castrillion Lab's work is aimed at understanding why endometrial or uterine cancers arise and spread, with an eye on prevention, earlier and more accurate diagnosis, improved treatments, and better overall patient outcomes.

We investigate how the immune system and gut microbiota influence brain function and behavior. We use molecular, behavioral, anatomical, and immunological approaches in the lab. In parallel, we collaborate with clinical groups to examine the role of inflammatory and gut-brain mediators in psychiatric illness.

The Foster Lab research program represents a “best in class” translational research approach in an enriched, multidisciplinary environment. Foster's academic activities include a strong translational research program, a comprehensive teaching portfolio, science outreach, contribution to local, national, and international peer review and knowledge translation.

The Center for Depression Research and Clinical Care (CDRC) is nationally recognized for its cutting-edge research in unipolar and bipolar depression. The research conducted within the center brings better understanding of the causes of depression, identifies effective new treatments, and improves existing ones.

Interrogating the genome to better understand the mechanisms causing autism spectrum disorder and other neurodevelopmental disorders and inform innovative therapies

Welcome to the Chalak Lab

Our lab is creating better experimental models that reveal how cancer cells metastasize and evade our immune system. We use these models to develop new drugs that engage our immune system to kill cancer cells.

We are interested in building small organic molecules and studying their functions in biological systems. Our lab started in 2004 using state-of-the-art tools to address challenging issues in the field of natural product synthesis. 

Deficiencies in DNA-damage signaling and repair pathways are fundamental to the etiology of most human cancers. Of the many types of DNA damage that occur within the cell, DNA double-strand breaks (DSBs) are particularly dangerous.

Elizabeth Chen Lab focuses research on cell-cell fusion, drosophila myoblast fusion, invasive membrane protrusions, actin binding and bundling proteins, and mechanoresponsive proteins.

Welcome to the Reproductive Genomics Laboratory (RGL) at UT Southwestern Medical Center where we innovate at the intersection of genomics, bioengineering, and data science to answer fundamental questions in reproductive biology.

Our primary research interest is to understand the emerging roles of the “unannotated genome,” which encodes a whole new class of uncharacterized microproteins. We focus on the relevance and function of this “dark proteome” in regulating development and disease.

Chen lab studies how dysregulation of RNA synthesis and degradation drives childhood cancers with the ultimate goal of identifying new therapeutic vulnerabilities to exploit in treating them.

Chen Lab is broadly interested in mechanisms of signal transduction, namely how a cell communicates with its surroundings and within itself.

Jonathan Cheng's Lab performs a comprehensive suite of outcome measures to assess peripheral nerve recovery and chronic neural interfacing in the research setting.

My lab has a long-time interest in understanding the mechanisms of transcription and gene regulation in mammalian cells using initially cell-free systems reconstituted with purified gene-specific transcription factors, general cofactors, and components of the general transcription machinery to recapitulate transcriptional events in vitro. 

Magnetic resonance spectroscopy (MRS) provides an effective tool for detecting bio-chemicals in living systems noninvasively. Dr. Choi’s lab focuses on technical and clinical development of MR spectroscopy (MRS) in the brain in vivo.

Ascending somatosensory circuitry that shapes the perception of touch and pain. We study the development, function and dysfunction of ascending somatosensory pathways.

The Chong Research group has been conducting clinical and translational research on cutaneous lupus including outcome measure development for clinical trials, biomarkers for diagnosis and prognosis, and disease outcomes.

The Chook Lab studies physical and cellular mechanisms of Kaps. Our long-term goals are to understand how the macromolecular nuclear traffic patterns coordinated by the 20 human Kaps contribute to overall cellular organization.