Our research is focused on mechanisms underlying acute kidney injury and sepsis. Our laboratory has implicated mitochondrial maintenance via PGC1alpha and NAD+ as a novel pathway for resilience against acute physiological stressors.
Dr. Park’s research focuses on the visual system and how the projection neurons in the retina, the retinal ganglion cell axons, find their targets and form synapses in the brain. He is investigating two key areas: 1) cellular and molecular mechanisms underlying the death of neurons and lack of regeneration in the central nervous system after injury and in degenerative diseases like glaucoma and 2) mechanisms by which neurons form proper connections with each other.
Our laboratory attracts scientists and collaborators with diverse backgrounds that range from mathematics to genetics, electrophysiology, brain functional imaging, or neuroscience, but with the common ability and shared vision to work on problems relevant to the human nervous and muscular systems and, more importantly, to the individuals afflicted by their diseases.
The mission of the Pedrosa Lab is to develop and implement new imaging methods that facilitate better morphologic and pathophysiologic characterization of diseases in the body for improved patient outcomes
Petroll Lab applies engineering approaches and design principles to the investigation of fundamental clinical and biological problems in ophthalmology, while providing training to graduate students, medical students, and post-docs.
The Pfeiffer Lab is interested in how the brain forms neural representations of experience, how those representations are consolidated into long-term memory, and how those representations can be later recalled to inform behavior.
We are developing inhibitors of pyrimidine biosynthesis and polyamine biosynthesis to treat malaria and African sleeping sickness. We study polyamine and nucleotide metabolism in African trypanosomes to learn about novel metabolism and regulation.
Pouratian Lab's primary mission is to explore basic human neuroscientific principles as well as identify brain mapping biomarkers of disease that can drive innovative approaches to restore function to patients with neurological and psychiatric diseases.
Dr. Prinz's research is focused on the tiny organelles within cells that do the cell’s work, much like the organs in a human body. He is best known for studies into the exchange of fats (also called lipids) between organelles at so-called membrane contact sites where organelles come in close contact within a cell.