The Oh lab is committed to elucidating how G protein-coupled Receptor (GPCR) works in regulating metabolism and identifying new avenues for developing therapeutics to treat metabolic syndromes such as type 2 diabetes, insulin resistance.
Our mission is to design and develop original devices, software solutions, and combined unique methodologies that translate into discoveries for next generation care.
Olson Lab studies muscle cells as a model for understanding how stem cells adopt specific fates and how programs of cell differentiation and morphogenesis are controlled during development.
Orchard Lab at UT Southwestern Medical Center
The Orth lab is interested in elucidation the activity of virulence factors from pathogenic bacteria so that we can gain novel molecular insight into eukaryotic signaling systems.
The Osborne Lab focuses on how regulation of miRNA and mRNA controls the branching of developing cells, and how disregulation of these pathways contributes to aggressive tumor behavior.
The main research focus of the Otwinowski lab is on developing computational and statistical
methods and protocols for macromolecular structure determination using X-ray crystallography.
Oz Lab combines imaging, interventional radiology, radiotracers (novel and known), and animal models to study physiology and disease pathophysiology.
The Pan laboratory uses Drosophila and mice as model systems to investigate size-control mechanisms in normal development and their pathological roles in cancer.
Our research is focused on mechanisms underlying acute kidney injury and sepsis. Our laboratory has implicated mitochondrial maintenance via PGC1alpha and NAD+ as a novel pathway for resilience against acute physiological stressors.
Welcome to the PARK Lab.
Our lab focuses on:
Dr. Park’s research focuses on the visual system and how the projection neurons in the retina, the retinal ganglion cell axons, find their targets and form synapses in the brain. He is investigating two key areas: 1) cellular and molecular mechanisms underlying the death of neurons and lack of regeneration in the central nervous system after injury and in degenerative diseases like glaucoma and 2) mechanisms by which neurons form proper connections with each other.
We study how cells duplicate their genomic material and how this process goes awry in disease.
The Parkland Outcomes after Prematurity Study research group focuses on the short- and long-term effects of preterm birth, to improve lifelong health outcomes for current and future patients.
Our laboratory has a particular interest in hepatic metabolism and its regulation by the immune system. We utilize genetic, epigenetic and proteomic approaches, combined with detailed physiological studies, to understand the complex mechanisms that causally link inflammation to metabolic dysfunction in obesity and fatty liver disease.
A major focus of the Patwardhan Lab is translational research into mechanisms of pain and potential treatment.
The mission of the Pedrosa Lab is to develop and implement new imaging methods that facilitate better morphologic and pathophysiologic characterization of diseases in the body for improved patient outcomes
Translational biophotonics for noninvasive detection of systemic disease.
Petroll Lab applies engineering approaches and design principles to the investigation of fundamental clinical and biological problems in ophthalmology, while providing training to graduate students, medical students, and post-docs.
The Pfeiffer Lab is interested in how the brain forms neural representations of experience, how those representations are consolidated into long-term memory, and how those representations can be later recalled to inform behavior.
Our lab uses tractable model viruses to learn about niche-specific factors that influence viral infection and evolution.
We are developing inhibitors of pyrimidine biosynthesis and polyamine biosynthesis to treat malaria and African sleeping sickness. We study polyamine and nucleotide metabolism in African trypanosomes to learn about novel metabolism and regulation.
The goal of our research is to identify key immune checkpoints of gastrointestinal disorders that could be targeted for therapeutic intervention and drug development.
