The global focus of the Pulmonary Physiology Laboratory is the study of pulmonary exercise physiology, particularly as it pertains to pulmonary disease, normal aging, obesity, ventilatory control during exercise, applied respiratory physiology, and clinical cardiopulmonary exercise testing. The Lab consists of three separate investigative laboratories: the pulmonary function laboratory, the cardiopulmonary exercise physiology laboratory, and the body composition laboratory including DEXA imaging for the determination of percent body fat, lean body mass, bone content, visceral fat, overall fat distribution, and their effects on breathing.
Qi lab specializes in investigating the structure and function of membrane proteins related to human diseases using cryo-EM, cell-based assays, and mouse models.
Xiaofeng Qi
Genetics, Development and DiseaseMolecular Biophysics
Qin Lab focuses on the development of novel synthetic transformations and strategies that will allow access to bioactive, complex natural products and efficient synthesis of pharmaceuticals and their derivatives.
Tian Qin, Ph.D.
Chemical synthesisBioactive natural productsCross CouplingsBioisosteres
We are interested in how membrane cholesterol controls diverse cellular signaling pathways to ensure lipid homeostasis, enable cell growth, and protect against infections.
We are broadly interested in how energy is regulated on a systems level during infection. Our current projects are focused on understanding the role that adipose tissue plays in the response to influenza and SARS-CoV2.
We are driven by the belief that the spatial organization of tissue provides a powerful window into cell-cell interactions, a crucial component of disease progression and response.
Dr. Rajji focuses on improving cognition in older adults with or at risk for dementia through brain stimulation, with cognitive, functional, and pharmacological modalities.
The Ranjan Lab’s mission is to develop and translate novel immunotherapies, with a particular focus on addressing malignant cancers in humans and animals.
Our lab is broadly focused on the cellular signaling that drives the interactions between the intracellular parasite Toxoplasma gondii and its varied hosts.
The Reinecker laboratory unravels and targets molecular mechanisms of key human genetic variants that cause chronic inflammatory diseases and cancer by creating novel genetic mouse and human organotypic model systems.
We are interested in the molecular mechanisms by which nuclear hormone receptors regulate lipid and carbohydrate metabolism in the liver, intestine, pancreatic islet, and central nervous system.
The Rice Lab uses structure, biochemistry, reconstitution, microscopy, computer modeling, and more to study the molecular mechanisms that generate and regulate microtubule dynamics.
We investigate the mechanism of neurotransmitter release using a variety of biophysical approaches, including NMR spectroscopy, X-ray crystallography, cryo-EM, molecular dynamics simulations and liposome fusion assays.
The Robertson Lab studies mitochondrial and metabolic homeostasis in the corneal epithelium and the role of homeostatic dysfunction in the pathophysiology of corneal disease.
The Rosen Lab seeks to understand the formation, regulation, functions and internal structures of membraneless cellular compartments termed biomolecular condensates.
The significance of our research is to show effective anti-Aβ42 antibody production in large animals and safety of DNA Aβ42 immunotherapy in these models to proceed with vaccination in patients at risk for Alzheimer’s disease.
Research in the Rothermel Laboratory focuses on deciphering the molecular mechanisms that control cardiac structure and function during normal development and in response to pathological stress.
