Rice Lab
The Rice Lab uses structure, biochemistry, reconstitution, microscopy, computer modeling, and more to study the molecular mechanisms that generate and regulate microtubule dynamics.
- Luke Rice, Ph.D.
The Rice Lab uses structure, biochemistry, reconstitution, microscopy, computer modeling, and more to study the molecular mechanisms that generate and regulate microtubule dynamics.
We investigate the mechanism of neurotransmitter release using a variety of biophysical approaches, including NMR spectroscopy, X-ray crystallography, cryo-EM, molecular dynamics simulations and liposome fusion assays.
Engineered hydrogel biomaterials to improve tissue regeneration and disease modelling
Roberts Lab focuses on understanding the cellular and circuit mechanisms for behavioral learning, learning from social experiences and from example.
The Robertson Lab studies mitochondrial and metabolic homeostasis in the corneal epithelium and the role of homeostatic dysfunction in the pathophysiology of corneal disease.
The Rohatgi Lab focuses on the role of reverse cholesterol transport in atheroprotection.
The Rosen Lab seeks to understand the formation, regulation, functions and internal structures of membraneless cellular compartments termed biomolecular condensates.
The significance of our research is to show effective anti-Aβ42 antibody production in large animals and safety of DNA Aβ42 immunotherapy in these models to proceed with vaccination in patients at risk for Alzheimer’s disease.
Research in the Rothermel Laboratory focuses on deciphering the molecular mechanisms that control cardiac structure and function during normal development and in response to pathological stress.
Our lab specializes in clinical and research informatics, with a diverse portfolio of projects that leverage electronic health record (EHR) data and multimodal research data to enhance clinical care and advance research in the neurosciences.
The Ruan Lab focuses its research on developing statistical methods and computational algorithms for multi-omics data with applications in complex human diseases.
Our lab studies how cells organize metabolic pathways to meet changing metabolic demands. We explore how higher-order enzyme assemblies and organelle dynamics create compartmentalized metabolic environments. By uncovering the spatiotemporal regulation of metabolism, we aim to reveal fundamental principles of metabolic control relevant to health and disease.
We study how biomolecular condensates organize gene regulation.
Saelices Lab employs crystallography and cryo-EM to study amyloid deposition and design anti-amyloid tools.
The Saha Lab.
Sakano Lab investigates FMRP's influence on auditory brainstem development in Fragile X Syndrome. We examine gene expression and its potential link to autism, auditory processing, hyperacusis, and tinnitus.
Our mission is to advance biomedical knowledge in Multiple Sclerosis and support investigators in Neurology using best practices and comprehensive biostatistics expertise.
We seek to understand how RNA/protein assemblies control cellular states, and how related pathways are hijacked by diseases of aging.
The Sandstrom Lab works to identify the fundamental molecular mechanisms through which the immune system can recognize pathogens and stress.
Satterthwaite Lab studies the signals that control B lymphocyte development, activation, and differentiation into antibody-secreting plasma cells, both normally and in autoimmune diseases such as lupus. We hope that by defining these events, we can reveal new approaches to modulate antibody responses therapeutically.
The Saunders Lab aims to advance our understanding of the bacterial domain of life using high throughput genetics to map the molecular interactions that underly cellular physiology.
The Saxena lab's research interests include Icodextin in high peritoneal transporters; Kremezin study in patients with chronic kidney disease; SV40 in focal segmental glomerulosclerosis; molecular studies in lupus nephritis.
The main focus in our laboratory is the identification and physiological characterization of adipocyte-specific gene products and the elucidation of pathways that are an integral part of the complex set of reactions that drive adipogenesis.
The Schoggins Lab studies innate immunity at the virus-host interface. We are interested in mechanisms of cellular antiviral defense and the role these responses play during viral disease.
What are the causes and consequences of cytoskeletal diversification?