Search Labs

We combine classical genetics with modern technology to understand human physiology and search for breakthrough treatments for diseases.

Our goal is to understand the importance of calcium signaling in development of neurodegenerative disorders.

The Bioinformatics Lab provides services to manage and analyze next-generation sequencing data.

Our mission is to innovate, develop, and apply biomedical technology to empower cancer research.

This facility is the home to five high field solution NMR spectrometers ranging from 500 MHz to 800 MHz and a Solid State 600 MHz DNP system, primarily in support of studies of macromolecular structure, function and dynamics.

Our research is largely aimed at understanding how an organism detects mechanical force.

The Bowen Lab focuses on the development of hybrid positron emission tomography (PET) (e.g. PET-CT and PET-MR) tools to enable precision imaging for the care and study of oncology, neurology, and cardiology patients.

The BRAIN lab, short for Brain Aging, Injury, and Modulation Lab, has two lines of research in the area of aging and neurodegenerative diseases. The lab investigates the later-in-life effects of traumatic brain injury, which involves understanding the potential risk associated with developing dementia and the underlying biological pathways. The lab also studies the effects of noninvasive brain stimulation in Alzheimer’s disease and related disorders with the goal of informing the development of new treatments.

The Brekken laboratory, located in the Hamon Center for Therapeutic Oncology Research, studies tumor-host interactions with a particular emphasis on extracellular matrix (ECM) and angiogenesis.

Our laboratory discovered a family of transcription factors called sterol regulatory element-binding proteins (SREBPs) that control cholesterol and fatty acid synthesis. 

• To understand how kidney cancer develops at the molecular level.
• To translate our findings into new treatments for kidney cancer patients.
• To train the next generation of physicians and scientists.

The Burgess lab uses Nuclear Magnetic Resonance spectroscopy and Mass Spectrometry in conjunction with stable isotope (non-radioactive) tracers to study how metabolic flux is altered by disease, pharmacology, or targeted genetic interventions.

Burstein Laboratory focuses on understanding the regulation of the inflammatory response at a molecular level, and elucidating how these events may participate in human disease.

The Busch Lab develops optical technologies for minimally and non-invasive bedside assessment of microvascular blood flow and oxygen saturation, allowing continuous assessment of aerobic metabolism. 

Buszczak laboratory seeks to gain new insights into mRNA translation, ribosome biogenesis and germ cell biology 

Our lab is working with to develop a gene therapy that would allow increased Ube3a expression in the paternal copy of the gene that causes Angelman syndrome.

My research interests include lipidomics, enzymology, drug discovery, and bioanalytical chemistry in the relation to ocular biochemistry, biophysics, and physiology. 

The Concussion, Acquired Brain Injury, and Neurodegeneration (CABIN) Laboratory, led by Kristin Wilmoth, Ph.D., investigates best practices for assessment and treatment of concussion and more severe traumatic brain injury, other acquired brain injuries such as stroke, and neurodegenerative conditions such as Alzheimer's disease.

The Collaborative for Advanced Clinical Techniques in UltraSound (CACTUS) constitutes a group of like-minded physicians, scientists, and technical experts dedicated to the advancement of clinical imaging, technical and translational research, and image-guided intervention in ultrasound.

We are interested in taking bioinformatics and data integration approaches to gain insights into cancer metabolism, inborn errors of metabolism, and lung neoplasm.