The Sharma lab is interested in investigating intermediary metabolism utilizing carbon-13 stable isotope tracers in conjunction with magnetic resonance spectroscopy (MRS), magnetic resonance imaging (MRI), and mass spectrometry (MS).
The overall goal of our laboratory is to discover the processes in endothelial cells that govern cardiovascular and metabolic health and disease.
Shay Lab is interested in the relationships between aging and cancer and have focused on the role of the telomeres and telomerase in these processes.
The ultimate aim of the Shiloh Lab is to contribute to the development of vaccines and treatments for Mycobacterium tuberculosis (Mtb).
Our primary goal in Sieber Lab is to understand the dynamic changes in metabolic programs that support developmental and disease progression.
We aim to globally understand how the physical and chemical properties of materials affect interactions with biological systems in the context of improving therapies.
The Sinnett Lab develops and assesses gene therapies for rare neurodevelopmental disorders.
Our work examines the interface between cancer and developmental biology
The Smith Lab strives to develop enabling tools for organic synthesis, allowing bioactive molecules of great complexity to be prepared in a concise and sustainable fashion.
The Solmonson lab is interested in how the placenta senses and achieves metabolic homeostasis between the adult and fetal compartments during pregnancy.
Dr. Song's laboratory focuses on understanding the mechanisms of cell death, including apoptosis, ferroptosis, pH-dependent cell death, and immunogenic cell death.
Our lab aim is to discover and translate findings into diagnostic and therapeutic solutions for patients with allergy.
The Sorrell laboratory utilizes integrative approaches that include metabolomics, transcriptomics, organoid cultures, live microcopy, and animal models, to investigate fundamental pathways that control the uptake of nutrients and the biosynthesis of macromolecules in proliferative cells.
The goal of the Center is to support pre-clinical research that uncovers the mechanisms of pediatric musculoskeletal disorders and explores potential new therapies.
Our laboratory is interested in investigating the molecular mechanisms of selenoproteins in health and disease.
The Stopschinski lab investigates molecular and cellular mechanisms that drive neurodegeneration in Alzheimer’s Disease and other tauopathies with the goal to find new diagnostic and therapeutic approaches for these conditions.
The Story Lab has a robust research portfolio that includes radiation-induced carcinogenesis associated with the unique environment of space, molecular markers of carcinogenic risk after radiation, intrinsic radiosensitivity, modulation of drug and radiation response by pentaazamacrocyclic ring compounds with dismutase activity, high-dose per fraction radiotherapy, charged particle radiotherapy, the mechanism(s) of action of Tumor Treating Fields, and the enhancement of cancer therapy through radiation and drug combination used concomitantly with Tumor Treating Fields.
The Stowe Lab conducts both bench and clinical research with the goal of deepening the understanding of the etiology of stroke as well as finding better therapies for those who have suffered a stroke.
The main goals of the Strand Lab are to create accurate cellular atlases of the human and mouse lower urinary tract, characterize the molecular and cellular alterations in human lower urinary tract disease, and design new mouse models.
We investigate epigenome regulation of nervous system development and homeostasis. We are particularly interested in understanding how disruption of these mechanisms lead to neurological disorders.
The vision of the lab is to further understand the pathogenesis of autoimmunity of the central nervous system through basic science and translational research.
