The Bartelt Lab is focused on understanding the epigenetic basis of cerebellar neurodegenerative disorders to develop holistic gene therapies. Using single-cell and spatial sequencing approaches, we profile healthy and diseased states to identify gene regulatory mechanisms in disease and utilize functional genomic tools to advance therapeutic approaches.
Our laboratory has characterized many of the transporters responsible for proximal tubule acidification and solute transport
The Beckham lab is a dynamic multidisciplinary laboratory that studies viral pathogenesis and neuroimmune responses.
Dr. Bedimo studies strategies for optimally managing drug-resistant HIV patients, analyzing metabolic abnormalities in HIV patients, and studying the effects of HCV co-infection.
We combine classical genetics with modern technology to understand human physiology and search for breakthrough treatments for diseases.
The Bezerra Lab current studies investigate how developmental defects increase the susceptibility of the biliary epithelium to infectious and toxic insults.
The Bioinformatics Lab provides services to manage and analyze next-generation sequencing data.
This facility is the home to five high field solution NMR spectrometers ranging from 500 MHz to 800 MHz and a Solid State 600 MHz DNP system, primarily in support of studies of macromolecular structure, function and dynamics.
The Bowen Lab focuses on the development of hybrid positron emission tomography (PET) (e.g. PET-CT and PET-MR) tools to enable precision imaging for the care and study of oncology, neurology, and cardiology patients.
The Brekken laboratory, located in the Hamon Center for Therapeutic Oncology Research, studies tumor-host interactions with a particular emphasis on extracellular matrix (ECM) and angiogenesis.
Our laboratory discovered a family of transcription factors called sterol regulatory element-binding proteins (SREBPs) that control cholesterol and fatty acid synthesis.
Psychoneuroendocrine Research Program (PNE) at UT Southwestern Medical Center.
Dr. Brunoni's research focuses on developing innovative therapeutic strategies using transcranial direct current stimulation, transcranial magnetic stimulation, and other neuromodulation techniques for treating major depressive disorder, bipolar disorder, OCD, schizophrenia, and post-COVID cognitive symptoms.
The Burgess lab uses Nuclear Magnetic Resonance spectroscopy and Mass Spectrometry in conjunction with stable isotope (non-radioactive) tracers to study how metabolic flux is altered by disease, pharmacology, or targeted genetic interventions.
Burstein Laboratory focuses on understanding the regulation of the inflammatory response at a molecular level, and elucidating how these events may participate in human disease.
The Busch Lab develops optical technologies for minimally and non-invasive bedside assessment of microvascular blood flow and oxygen saturation, allowing continuous assessment of aerobic metabolism.
Buszczak laboratory seeks to gain new insights into mRNA translation, ribosome biogenesis and germ cell biology
Our lab is working with to develop a gene therapy that would allow increased Ube3a expression in the paternal copy of the gene that causes Angelman syndrome.
My research interests include lipidomics, enzymology, drug discovery, and bioanalytical chemistry in the relation to ocular biochemistry, biophysics, and physiology.
We are interested in taking bioinformatics and data integration approaches to gain insights into cancer metabolism, inborn errors of metabolism, and lung neoplasm.
